Pregnancy and Childbirth After Sertoli-Leydig Cell Tumor Resection: A Case Study and Literature Review

抗癌研究 Pub Date : 2022-07-27 DOI:10.26689/par.v6i4.4092

Li-jun Mu, Lihong Zhu

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Abstract

Objectives: To explore the clinical manifestations and pathological features in the biopsy of ovarian Sertoli-Leydig cell tumor, as well as to improve the clinical understanding of the disease. Methods: A case of pregnancy and childbirth after Sertoli-Leydig cell tumor resection was retrospectively analyzed. The patients’ clinical data were collected, including the clinical manifestations, postoperative biopsy results, auxiliary examination results, immunohistochemical results, treatment, and prognosis of the patient. Results: (1) SLCT occurred unilaterally; (2) according to the International Federation of Obstetrics and Gynecology (FIGO), the clinical staging was stage IA; according to the pathological classification of malignant tumors, it was grade ? (moderately differentiated); (3) a healthy female live baby was delivered. Conclusion: Such tumors are rare low-grade malignancies and are even rarer in pregnancy. An increase in preoperative testosterone levels with positive ultrasonography results can be used to assist diagnosis; however, postoperative biopsy pathology remains the “gold standard” for the diagnosis of SLCTs. The definite diagnosis of SLCTs is of great significance for surgical planning and prognostic evaluation.

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Sertoli Leydig细胞肿瘤切除术后的妊娠和分娩：病例研究和文献综述

目的：探讨卵巢支持细胞间质瘤活检的临床表现和病理特点，提高临床对该病的认识。方法：回顾性分析1例睾丸支持细胞肿瘤切除术后妊娠分娩的病例。收集患者的临床资料，包括患者的临床表现、术后活检结果、辅助检查结果、免疫组织化学结果、治疗和预后。结果：（1）SLCT单侧发生；（2）根据国际妇产科联合会（FIGO），临床分期为IA期；根据恶性肿瘤的病理分类，它是分级的？（中度分化）；（3）一个健康的活女婴出生了。结论：此类肿瘤是罕见的低度恶性肿瘤，在妊娠期更为罕见。术前睾酮水平升高，超声检查结果呈阳性，可用于辅助诊断；然而，术后活检病理学仍然是SLCT诊断的“金标准”。SLCT的明确诊断对手术计划和预后评估具有重要意义。

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抗癌研究

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