How can bioinformatics contribute to the routine application of personalized precision medicine?

IF 1 Q4 PHARMACOLOGY & PHARMACY

Expert Review of Precision Medicine and Drug Development Pub Date : 2020-05-03 DOI:10.1080/23808993.2020.1758062

C. Carretero-Puche, Santiago García-Martín, R. García-Carbonero, G. Gómez-López, F. Al-Shahrour

引用次数: 2

Abstract

The last few years have witnessed the emergence of personalized precision medicine (PPM), a novel approach to improve clinical decisions, integrating individual multi-omic profiles, and heterogeneo...

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生物信息学如何为个性化精准医学的常规应用做出贡献？

过去几年见证了个性化精准医学（PPM）的出现，这是一种改进临床决策的新方法，整合了个体多组学特征和异质性。。。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Expert Review of Precision Medicine and Drug Development PHARMACOLOGY & PHARMACY-

CiteScore

2.30

自引率

0.00%

发文量

期刊介绍： Expert Review of Precision Medicine and Drug Development publishes primarily review articles covering the development and clinical application of medicine to be used in a personalized therapy setting; in addition, the journal also publishes original research and commentary-style articles. In an era where medicine is recognizing that a one-size-fits-all approach is not always appropriate, it has become necessary to identify patients responsive to treatments and treat patient populations using a tailored approach. Areas covered include: Development and application of drugs targeted to specific genotypes and populations, as well as advanced diagnostic technologies and significant biomarkers that aid in this. Clinical trials and case studies within personalized therapy and drug development. Screening, prediction and prevention of disease, prediction of adverse events, treatment monitoring, effects of metabolomics and microbiomics on treatment. Secondary population research, genome-wide association studies, disease–gene association studies, personal genome technologies. Ethical and cost–benefit issues, the impact to healthcare and business infrastructure, and regulatory issues.