Computation of the Balance of Monovalent Ion Fluxes in the U937 Cell as an Example of a Proliferating Animal Cell

Abstract

This paper was prepared by Alexey A. Vereninov for an online presentation in connection with his 90th birthday. Unfortunately, his health did not allow him to take part in this online meeting, but he hoped that his presentation would still be published. To our deep regret, he passed away on July 5, 2022. All his life, A. Vereninov worked at the Institute of Cytology of the Russian Academy of Sciences where, from 1986 to 2019, he headed the Laboratory of Cell Physiology. Alexey Vereninov was interested in answering the fundamental questions regarding ionic homeostasis in animal cells. In the last years of his life, he became particularly interested in the quantitative analysis of monovalent ion fluxes through the cell membrane. The calculation algorithm was developed by Alexey together with his brother Igor A. Vereninov, professor at St. Petersburg State Polytechnical University. The results of their work in recent years are summarized in this paper.