Clinical features and prognostic analysis of children with medulloblastoma in a single center in China

Yan Su, Shuai Zhu, Jing Qin, M. Ge, Yuan-qi Ji, Jian Gong, Tong Yu, Libing Fu, Zhikai Liu, Xiao-li Ma
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Abstract

Background: Medulloblastoma (MB) is the most common malignant pediatric brain tumor. This study systematically summarized the clinical characteristics and prognosis of children with MB respectively. Univariate survival analysis identified age <3 years and the absence of radiotherapy as poor prognostic factors (both P<0.05). Conclusions: Survival outcomes were good among patients with MB (MB) in our center. Young age and the omission of radiotherapy may be predictive of poor outcomes.
中国单中心儿童髓母细胞瘤的临床特点及预后分析
背景:髓母细胞瘤是儿童最常见的恶性脑肿瘤。本研究系统总结了小儿MB的临床特点和预后。单因素生存分析发现年龄<3岁和未接受放疗是不良预后因素(P<0.05)。结论:本中心MB患者的生存结局良好。年轻和未接受放射治疗可能预示预后不良。
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