Ida Nurwati, R. Ar, D. Hermawan, Betty Saptiwi, D. R. Budiani, Jarot Subandono, M. Martini, M. Muthmainah, Sarsono Sarsono, S. Handayani
{"title":"POTENTIAL OF JAMBLANG (Syzygium cumini L.) LEAF EXTRACT ON BODY WEIGHT OF\n WISTAR RATS METABOLIC SYNDROME MODEL","authors":"Ida Nurwati, R. Ar, D. Hermawan, Betty Saptiwi, D. R. Budiani, Jarot Subandono, M. Martini, M. Muthmainah, Sarsono Sarsono, S. Handayani","doi":"10.31983/jrk.v10i2.7703","DOIUrl":null,"url":null,"abstract":"Jamblang (Syzygium cumini L.) leaves contain several phytochemical\n compounds. These phytochemicals are thought to have roles as\n antihyperglycemic, antihyperlipidemic, and antioxidant agents. This study\n aims to prove that there is an effect of giving ethanolic extract of\n jamblang leaves on body weight (BW) of metabolic syndrome (MS) Wistar rats\n induced by high-fat high-fructrose diet (HFFD) and injection of\n Streptozotocin (STZ)-Nicotinamide (Na), to determine different doses effect\n on the weight of Wistar rats. Laboratory experimental research with pre-post\n test control group. Samples were 8 weeks male Wistar (Rattus noverigicus)\n weighing 150-200 grams chosen by purposive random sampling method.\n Thirty rats were divided into 5 groups, each consisting of 6 rats. Normal\n group, metabolic syndrome group, 3 treatment groups MS were given jamblang\n leaf extract 100 mg/KgBW, 150mg/KgBW, 200mg/KgBW for 28 days. Data were\n analyzed by one way ANOVA test and repeated ANOVA test. The study showed an\n ethanolic extract of Jamblang leaves can reduce weight loss in Wistar rats\n with a metabolic syndrome model, and that the best dose used in this\n experiment is 150 mg/kgBW per day in Wistar rats with a metabolic syndrome\n model.","PeriodicalId":52993,"journal":{"name":"Jurnal Riset Kesehatan","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jurnal Riset Kesehatan","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31983/jrk.v10i2.7703","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Jamblang (Syzygium cumini L.) leaves contain several phytochemical
compounds. These phytochemicals are thought to have roles as
antihyperglycemic, antihyperlipidemic, and antioxidant agents. This study
aims to prove that there is an effect of giving ethanolic extract of
jamblang leaves on body weight (BW) of metabolic syndrome (MS) Wistar rats
induced by high-fat high-fructrose diet (HFFD) and injection of
Streptozotocin (STZ)-Nicotinamide (Na), to determine different doses effect
on the weight of Wistar rats. Laboratory experimental research with pre-post
test control group. Samples were 8 weeks male Wistar (Rattus noverigicus)
weighing 150-200 grams chosen by purposive random sampling method.
Thirty rats were divided into 5 groups, each consisting of 6 rats. Normal
group, metabolic syndrome group, 3 treatment groups MS were given jamblang
leaf extract 100 mg/KgBW, 150mg/KgBW, 200mg/KgBW for 28 days. Data were
analyzed by one way ANOVA test and repeated ANOVA test. The study showed an
ethanolic extract of Jamblang leaves can reduce weight loss in Wistar rats
with a metabolic syndrome model, and that the best dose used in this
experiment is 150 mg/kgBW per day in Wistar rats with a metabolic syndrome
model.