Clinico-pathological Profile and Immediate Hospital Outcome of Acute Pancreatitis

Journal of medicine Pub Date : 2022-02-03 DOI:10.3329/jom.v23i1.57933

MS Alam, M. Rahman, A. Kabir, Md. Uzzwal Mallik, Saima Azad

{"title":"Clinico-pathological Profile and Immediate Hospital Outcome of Acute Pancreatitis","authors":"MS Alam, M. Rahman, A. Kabir, Md. Uzzwal Mallik, Saima Azad","doi":"10.3329/jom.v23i1.57933","DOIUrl":null,"url":null,"abstract":"Background: Acute pancreatitis (AP) is a significant cause of acute abdominal pain, morbidity andhospitalization. Knowing the details of the clinico-pathological presentation and outcome of the diseasemay aid the better understanding of the disease.Objective: The study was designed to assess the clinico-pathological profile and to estimate immediatehospital outcome of acute pancreatitis patients admitted into a tertiary care hospital.\nMaterials and Methods: This hospital based cross-sectional type of observational study was conductedat Dhaka Medical College Hospital (DMCH), for one-year period (June 2018-May 2019).Total 106established cases of acute pancreatitis were included in this study. Data was analyzed by the SPSS 22Windows version and graph & chart were expressed by using SPSS 22 and MS Excel. The Result waspresented with tables and charts.\nResults: Among 106 patients, mean age of the patients was 42.5 ±11.3 SD (years), with male predominance(male: female-1.2:1). All of the patients complained abdominal pain (100%) while anorexia (48.1%), 43.4%had vomiting and 31.1% had fever. Regarding clinical signs, abdominal distension (45.3%), paralytic ileus(34.9%) and dehydration (43.4%) were found to be the major clinical signs. The common location of painwas in epigastric region (73.6%) with radiation to back in 20.8% patients. Pain was severe agonizing innature in 76.4% cases. Of all, gall stone disease (17.0%) was the most prevalent cause. According toAPACHE-II score, 74.5% patients had mild pancreatitis (APACHE-II <8) while according to Glasgowcriteria, 66.0% had mild disease (Glasgow score <3). Mean APACHE-II score was 7.07±2.50 and Glasgowscore was 2.90±2.33. Mean hospital stays were 8.9±3.6 days and NPO (nothing per oral) 4.9±1.9 days.Among the patients, 77.4% patients were alive and mortality rate was 22.6%.\nConclusion: Although, a larger portion of the patients had no identifiable cause but gall stone was themost common etiology. Pain commonly located in epigastric region with radiation to back. Of all thecases, more than sixty percent of the patients had mild pancreatitis estimated by APACHE II score andGlasgow score. Mean hospital stays were about 9 days and nothing per oral was about 5 days. Overallmortality rate was 22.6%.\nJ MEDICINE 2022; 23: 24-29","PeriodicalId":76013,"journal":{"name":"Journal of medicine","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3329/jom.v23i1.57933","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Acute pancreatitis (AP) is a significant cause of acute abdominal pain, morbidity andhospitalization. Knowing the details of the clinico-pathological presentation and outcome of the diseasemay aid the better understanding of the disease.Objective: The study was designed to assess the clinico-pathological profile and to estimate immediatehospital outcome of acute pancreatitis patients admitted into a tertiary care hospital. Materials and Methods: This hospital based cross-sectional type of observational study was conductedat Dhaka Medical College Hospital (DMCH), for one-year period (June 2018-May 2019).Total 106established cases of acute pancreatitis were included in this study. Data was analyzed by the SPSS 22Windows version and graph & chart were expressed by using SPSS 22 and MS Excel. The Result waspresented with tables and charts. Results: Among 106 patients, mean age of the patients was 42.5 ±11.3 SD (years), with male predominance(male: female-1.2:1). All of the patients complained abdominal pain (100%) while anorexia (48.1%), 43.4%had vomiting and 31.1% had fever. Regarding clinical signs, abdominal distension (45.3%), paralytic ileus(34.9%) and dehydration (43.4%) were found to be the major clinical signs. The common location of painwas in epigastric region (73.6%) with radiation to back in 20.8% patients. Pain was severe agonizing innature in 76.4% cases. Of all, gall stone disease (17.0%) was the most prevalent cause. According toAPACHE-II score, 74.5% patients had mild pancreatitis (APACHE-II <8) while according to Glasgowcriteria, 66.0% had mild disease (Glasgow score <3). Mean APACHE-II score was 7.07±2.50 and Glasgowscore was 2.90±2.33. Mean hospital stays were 8.9±3.6 days and NPO (nothing per oral) 4.9±1.9 days.Among the patients, 77.4% patients were alive and mortality rate was 22.6%. Conclusion: Although, a larger portion of the patients had no identifiable cause but gall stone was themost common etiology. Pain commonly located in epigastric region with radiation to back. Of all thecases, more than sixty percent of the patients had mild pancreatitis estimated by APACHE II score andGlasgow score. Mean hospital stays were about 9 days and nothing per oral was about 5 days. Overallmortality rate was 22.6%. J MEDICINE 2022; 23: 24-29

查看原文本刊更多论文

急性胰腺炎的临床病理特征和即时医院转归

背景：急性胰腺炎（AP）是引起急性腹痛、发病和住院的重要原因。了解疾病的临床病理表现和结果的细节可能有助于更好地了解疾病。目的：本研究旨在评估三级护理医院收治的急性胰腺炎患者的临床病理特征，并评估其即时住院结果。材料和方法：这项基于医院的横断面观察性研究在达卡医学院医院（DMCH）进行，为期一年（2018年6月至2019年5月）。本研究共纳入106例确诊的急性胰腺炎病例。数据采用SPSS 22Windows软件进行分析，图表采用SPSS 22软件和MS Excel进行表达。结果用表格和图表表示。结果：106例患者的平均年龄为42.5±11.3 SD（年），以男性为主（男性：女性-1.2:1），所有患者均主诉腹痛（100%），厌食（48.1%），呕吐43.4%，发烧31.1%。在临床症状方面，腹胀（45.3%）、麻痹性肠梗阻（34.9%）和脱水（43.4%）是主要的临床症状。最常见的疼痛部位是上腹部（73.6%），20.8%的患者是背部放射。76.4%的患者的疼痛表现为严重的内脏疼痛。胆囊结石是最常见的病因（17.0%）。根据APACHE-II评分，74.5%的患者患有轻度胰腺炎（APACHE-II<8），而根据Glasgow标准，66.0%的患者患有轻微疾病（Glasgow评分<3）。平均APACHE-II评分为7.07±2.50，Glasgow评分为2.90±2.33。平均住院时间为8.9±3.6天，NPO（每次口服无）为4.9±1.9天。在这些患者中，77.4%的患者是活着的，死亡率为22.6%。结论：虽然大部分患者没有明确的病因，但胆结石是最常见的病因。疼痛通常位于上腹部，背部有辐射。根据APACHE II评分和Glasgow评分，超过60%的患者患有轻度胰腺炎。平均住院时间约为9天，每次口服约为5天。总体死亡率为22.6%。《医学杂志》2022；23:24-29

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of medicine

自引率

0.00%

发文量