Impact of split X-jaw technique on target volume coverage and organ at risk sparing in prostate cancer: a comparative dosimetric study

IF 0.3 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
G. Sarma, J. Nath, Shrayanti Goswami, Pranjal Goswami, S. Sharma, A. Kalita
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引用次数: 1

Abstract

Abstract Introduction: The Varian Trilogy linear accelerator’s multi-leaf collimator moves on a carriage with a maximum leaf span of 15 cm. The traditional open and limited X-jaw technique of volumetric-modulated arc radiotherapy (VMAT) yields a relatively compromised dose distribution within the planning target volume (PTV) region. This study aimed to determine whether the split X-jaw planning technique for VMAT improves plan quality regarding target dose coverage and organs at risk (OAR) sparing for PTVs that require a field size of more than 15 cm in the X-jaw direction in prostate cancer patients. Method: Computed tomography data sets from 15 patients with prostate cancer were enrolled in the study. Only the PTVs requiring a field size larger than 18 cm in the X-jaw position were considered, and a dose of 4500 cGy in 25 fractions was prescribed. For each case, three separate treatment plans were generated: open, limited and split X-jaw planning techniques with similar planning objectives Results: The split X-jaw technique resulted in statistically significant superior coverage of PTV when compared with the open (P < 0·0001) and limited methods (P < 0·001). The split technique delivered a lower dose to the OARs, although statistical significance could not be achieved. D2% (cGy) was lowest for the PTV in the split technique (4684·8 ± 18·16) and highest for the open technique (4710 ± 18·75), P < 0·001. Conclusion: The x-split jaw technique can replace the traditional open X-jaw practice of VMAT for PTVs requiring an X-jaw width of more than 15 cm in the Varian linear accelerator.
分割x颚技术对前列腺癌靶体积覆盖和危险器官保留的影响:一项比较剂量学研究
摘要简介:瓦里安三部曲直线加速器的多叶片准直器在一个最大叶片跨度为15厘米的托架上移动。传统的体积调制电弧放射治疗(VMAT)的开放和有限x颌技术在计划靶体积(PTV)区域内产生相对折衷的剂量分布。本研究旨在确定用于VMAT的分割x颌计划技术是否提高了前列腺癌患者在x颌方向需要大于15 cm视野的ppv的靶剂量覆盖和危险器官(OAR)保留的计划质量。方法:15例前列腺癌患者的计算机断层扫描数据集被纳入研究。仅考虑在x颌位置需要大于18 cm场的ptv,并规定25份剂量为4500 cGy。对于每个病例,生成了三种独立的治疗方案:开放、有限和分裂x颌计划技术,具有相似的计划目标。结果:与开放方法(P < 0.001)和有限方法(P < 0.001)相比,分裂x颌技术的PTV覆盖率具有统计学意义上的优势。劈裂技术给桨叶的剂量较低,但没有达到统计学意义。劈开技术PTV的D2% (cGy)最低(4688.4±18.16),开放技术最高(4710±18.75),P < 0.001。结论:x裂颌技术可替代传统的开放式x颌VMAT治疗在瓦里安直线加速器下x颌宽度大于15cm的PTVs。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Radiotherapy in Practice
Journal of Radiotherapy in Practice RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
CiteScore
0.80
自引率
0.00%
发文量
36
期刊介绍: Journal of Radiotherapy in Practice is a peer-reviewed journal covering all of the current modalities specific to clinical oncology and radiotherapy. The journal aims to publish research from a wide range of styles and encourage debate and the exchange of information and opinion from within the field of radiotherapy practice and clinical oncology. The journal also aims to encourage technical evaluations and case studies as well as equipment reviews that will be of interest to an international radiotherapy audience.
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