Immune Response and Susceptibility to SARS-CoV2 Virus in Children

International journal of pediatrics and child health Pub Date : 2021-03-15 DOI:10.12974/2311-8687.2021.09.2

M. Merchán, Rosa Silva, D. Velandia

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Abstract

: The COVID-19 disease that was first discovered in Wuhan-China province, also called severe acute respiratory syndrome, is a serious public health concern in the 21st century. This disease affects the respiratory system and its causal agent is the SARS-CoV2 virus, which is part of the family of beta-corona viruses that many associate with the bat. This virus not only affects the population that is considered vulnerable but also affects young adults and children. The objective of the present review is to describe the characteristics of the immune response and susceptibility in children with SARS-COV2. We examined articles in the Elsevier, Google Scholar, PubMed and Scielo databases regarding the immune systems of children with the disease of COVID-19 and the physio-pathological mechanisms of SARS-CoV2 that contribute to illness in this population. Although the capacity of infection of SARS-CoV2 in children is very high, the mechanism of the virus against pathogenicity in this population group is not clear. The objective of the present review is to describe the characteristics of the immune response and susceptibility in children with SARS-COV2

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儿童对SARS-CoV2病毒的免疫反应和易感性

：首次在中国武汉发现的新冠肺炎疾病，也称为严重急性呼吸综合征，是21世纪严重的公共卫生问题。这种疾病影响呼吸系统，其病原体是严重急性呼吸系统综合征冠状病毒2型，它是许多与蝙蝠有关的β冠状病毒家族的一部分。这种病毒不仅影响被认为脆弱的人群，还影响年轻人和儿童。本综述的目的是描述严重急性呼吸系统综合征冠状病毒2型儿童的免疫反应和易感性特征。我们研究了爱思唯尔、谷歌学者、PubMed和Scielo数据库中关于新冠肺炎疾病儿童免疫系统以及导致该人群疾病的SARS-CoV2的生理病理机制的文章。尽管儿童感染严重急性呼吸系统综合征冠状病毒2型的能力非常高，但该病毒在该人群中对抗致病性的机制尚不清楚。本综述的目的是描述严重急性呼吸系统综合征冠状病毒2型儿童的免疫反应和易感性特征

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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International journal of pediatrics and child health

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