Asupan vitamin A, vitamin C, vitamin E, BCAA dan kaitannya dengan kadar hs-CRP pada member fitness center dewasa

Qoniatu Zulfa, Deny Yudi Fitranti, Hartanti Sandi Wijayanti, Etika Ratna Noer
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Abstract

Excessive physical exercise can stimulate proinflammatory cytokines expressions and increases high sensitivity C-Reactive Protein (hs-CRP). Branched Chain Amino Acids (BCAA) and vitamins A, C, and E are antioxidant mechanisms to reduce oxidative stress. This study analyzes the correlation between vitamin A, C, E, and BCAA intake with hs-CRP. The study design was cross-sectional, which was conducted in Semarang. Participants were 48 men aged 20-43 years. Sampling used consecutive sampling. Data were collected using food recall 3x24h to assess dietary intake and laboratory tests using the Immunoturbidimetric method to determine hs-CRP levels. Data were statistically analyzed using Spearman-Rank and multiple linear regression. The result showed that the subject with high-risk categories of hs-CRP was 18,8%. The intake of BCAA was 10,8% from supplements. Most subjects had an excessive intake of vitamin A but did not meet the needs of vitamins C and E. There was no correlation between BCAA intake (p= 0,681) and vitamin C intake (p= 0,137) with hs-CRP levels. However, there was a negative correlation between vitamin A (p= 0,003) and vitamin E (p= 0,013) intake with hs-CRP levels. Multivariate analysis showed that the intake of vitamin A associated with hs-CRP levels of 8,1% (p= 0,028). In conclusion, vitamin A intake is the most influential factor in hs-CRP levels in fitness center members. 
过度的体育锻炼可以刺激促炎细胞因子的表达,增加高敏c反应蛋白(hs-CRP)。支链氨基酸(BCAA)和维生素A、C和E是减少氧化应激的抗氧化机制。本研究分析了维生素A、C、E和BCAA摄入量与hs-CRP之间的关系。研究设计是横断面的,在三宝垄进行。参与者是48名年龄在20-43岁之间的男性。抽样采用连续抽样。数据收集采用食品召回3x24h评估膳食摄入量,实验室检测采用免疫比浊法测定hs-CRP水平。采用Spearman-Rank和多元线性回归对数据进行统计学分析。结果显示,hs-CRP高危类别的受试者占18.8%。BCAA的摄入量为10.8%来自补充剂。大多数受试者维生素A摄入过量,但维生素C和e的需求不满足。BCAA摄入量(p= 0.681)和维生素C摄入量(p= 0.137)与hs-CRP水平没有相关性。然而,维生素a (p= 0.003)和维生素E (p= 0.013)摄入量与hs-CRP水平呈负相关。多变量分析显示,维生素A摄入量与hs-CRP水平相关8.1% (p= 0.028)。综上所述,维生素A摄入量是影响健身中心成员hs-CRP水平的最重要因素。
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