A review of sulfoxaflor, a derivative of biological acting substances as a class of insecticides with a broad range of action against many insect pests

Q3 Agricultural and Biological Sciences

Journal of Entomological and Acarological Research Pub Date : 2018-12-13 DOI:10.4081/jear.2018.7836

L. Bacci, S. Convertini, B. Rossaro

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引用次数: 24

Abstract

Sulfoxaflor is an insecticide used against sap-feeding insects (Aphididae, Aleyrodidae) belonging to the family of sulfoximine; sulfoximine is a chiral nitrogen-containing sulphur (VI) molecule; it is a sub-group of insecticides that act as nicotinic acetylcholine receptor (nAChR) competitive modulators. Sulfoxaflor binds to nAChR in place of acetylcholine and acts as an allosteric activator of nAChR. Thanks to its mode of action resistance phenomena are uncommon, even few cases of resistance were reported. It binds to receptors determining uncontrolled nerve impulses followed by muscle tremors to which paralysis and death follows. Sulfoxaflor acts on the same receptors of neonicotinoids as nicotine and butenolides, but it binds differently. It binds to insects nAChRs more strongly than to mammals’ ones, so it is much less toxic for mammals and man. Sulfoxaflor is supposed to have a low environmental impact and is not much aggressive against non-target species. Unfortunately, it is toxic to impollinator insects, so it must be used only in compliance with a series of legislative norms. At present sulfoxaflor can be considered one of the most interesting products to be used in fighting against agriculture insect pests.

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亚砜虫胺是一类生物作用物质的衍生物，对多种害虫具有广泛的作用

磺酰草胺是一种杀虫剂，用于防治磺酰亚胺科的食液昆虫（蚜虫科，蚜虫科）；磺酰亚胺是一种手性含氮硫（VI）分子；它是作为烟碱乙酰胆碱受体（nAChR）竞争调节剂的一个子组杀虫剂。磺酰草醚取代乙酰胆碱与nAChR结合，并作为nAChR的变构激活剂。由于其作用方式，阻力现象并不常见，甚至很少有阻力的报道。它与受体结合，决定不受控制的神经冲动，随后是肌肉震颤，随后是瘫痪和死亡。磺基恶唑对新烟碱类受体的作用与尼古丁和丁烯内酯相同，但结合不同。与哺乳动物相比，它与昆虫nAChRs的结合更强，因此对哺乳动物和人类的毒性要小得多。磺草醚被认为对环境影响较小，对非目标物种的攻击性也不大。不幸的是，它对催芽昆虫有毒，因此只能在符合一系列立法规范的情况下使用。目前，磺基恶唑可以被认为是最有趣的产品之一，用于对抗农业害虫。

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来源期刊

Journal of Entomological and Acarological Research Agricultural and Biological Sciences-Insect Science

CiteScore

1.00

自引率

0.00%

发文量

审稿时长

10 weeks

期刊介绍： The Journal of Entomological and Acarological Research (JEAR), formerly the Bollettino di Zoologia Agraria e di Bachicoltura of the Institute of Entomology of the Università degli Studi, Milano, was founded in 1928 by Remo Grandori. Thereafter, Minos Martelli and Luciano Süss hold the direction of the Journal until December 2011. In January 2012 the Editor decided for the new open-access on-line version of JEAR. The Journal publishes original research papers concerning Arthopods, but reviews, editorials, technical reports, brief notes, conference proceeding, letters to the Editor, book reviews are also welcome. JEAR has four main areas of interest: -Entomology (systematics; morphology; biology; biotechnology; agriculture, ornamental and forest entomology; applied entomology; integrated pest management; biological control; apiculture and apidology; medical, urban and veterinary entomology; etc.) -Stored product pests (biology; integrated pest management; etc.) -Insect Ecology (behaviour; biodiversity; taxonomy; plant insect interaction and ecosystems; biological control; alien species; etc.) -Acarology (systematics; morphology; biology; parasitology; control; etc.) The publication of manuscripts is subject to the approval of the Section Editor who has knowledge of the field discussed in the manuscript in accordance with the principles of Peer Review; referees will be selected from the Editorial Board or among qualified scientists of the international scientific community. Articles must be written in English and must adhere to the guidelines and details contained in the Instructions to Authors.