Epidemiological profile of young patients with squamous cell carcinoma in northeast Brazil

Q1 Medicine

Journal of Investigative and Clinical Dentistry Pub Date : 2019-07-27 DOI:10.1111/jicd.12436

Karen Rayssa Borba Ribeiro, Cledinaldo Lira Júnior, Sandra Aparecida Marinho, Sérgio Henrique Gonçalves de Carvalho, Gustavo Gomes Agripino, Dmitry José de Santana Sarmento

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引用次数: 5

Abstract

Aim

The aim of the present study was to delineate the epidemiological profile of young patients with squamous cell carcinoma (SCC) treated at a healthcare service in northeastern Brazil.

Methods

A cross-sectional study was performed involving the quantitative analysis of 51 medical records from patients diagnosed with SCC between 1998 and 2013. All patients aged ≤50 years were included in the study. Statistical analysis involved Pearson's χ²-test, Fisher's exact test, and the Mann-Whitney U-test, with the level of significance set at 5% (P < .05).

Results

The mean age was 46 ± 7.94 years, and males accounted for 80.4% of the sample. The tongue was the most affected site (37.3%). Most tumors were classified as stage III (26.3%) or IV (42.1%). Surgery associated with chemotherapy was the most common therapeutic approach (39.3%). Female patients had a lower mean age (P = .013) and less advanced clinical staging (P = .022). Smoking was more associated with male sex (P = .043).

Conclusion

SCC in young patients is more common in males aged 46 ± 7.94 years, with the tongue being the most affected anatomic site. Important differences were found in clinical-epidemiological features between young men and women.

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巴西东北部年轻鳞状细胞癌患者的流行病学分析。

目的本研究的目的是描述在巴西东北部医疗服务机构接受治疗的年轻鳞状细胞癌（SCC）患者的流行病学特征。方法进行横断面研究，对1998年至2013年间诊断为鳞状细胞癌的51份病历进行定量分析。所有年龄≤50岁的患者均纳入研究。统计分析包括Pearsonχ2检验、Fisher精确检验和Mann-Whitney U检验，显著性水平为5%（P＜0.05）。结果平均年龄为46±7.94岁，男性占样本的80.4%。舌头是受影响最严重的部位（37.3%）。大多数肿瘤分为III期（26.3%）或IV期（42.1%）。与化疗相关的手术是最常见的治疗方法（39.3%）。女性患者的平均年龄较低（P=0.013），临床分期较低（P=.022）。吸烟与男性更相关（P=.043）。结论年轻患者的SCC更常见年龄46±7.94岁的男性，其中舌头是受影响最大的解剖部位。年轻男性和女性在临床流行病学特征方面存在重要差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Investigative and Clinical Dentistry DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.90

自引率

0.00%

发文量

期刊介绍： Journal of Investigative and Clinical Dentistry (JICD) aims to publish quality, peer reviewed original research and topical reviews on all aspects of investigative and clinical dentistry and craniofacial research, including molecular studies related to oral health and disease. Although international in outlook, the Editor especially encourages papers from the Asia Pacific. The journal also aims to provide clinicians, scientists and students of dentistry with a knowledge transfer platform for rapid publication of reports through an international journal, which will be available free online until 2012. Its scope, therefore, is broad, inclusive and international, but with a particular focus on Asia Pacific. The Editor welcomes manuscripts in the following key thematic areas in oral and maxillofacial sciences: Community Dentistry and Oral Epidemiology, Conservative Dentistry, Dental Biomaterials, Dental Pedagogy, Endodontics and Traumatology, Implant Dentistry, Oral Biosciences, Oral and Maxillofacial Surgery, Oral Medicine, Oral Pathology and Oral Microbiology, Orthodontics, Oral Radiology, Oral Rehabilitation, Paedodontics, Periodontology and Periodontal Medicine.