Surgical Treatment of Gastric Malignancy in Chronic Kidney Disease Patient with Long-Term Haemodialysis

N. Kovalenko, A. I. Ivanov, S. R. Galeev, Viktoria V. Zhavoronkova, Alexey U. Nikolaev, M. Postolov, V. A. Suvorov, A. A. Klimchenko
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Abstract

Background. Gastric cancer is the world 5th top malignancy, with treatment success largely conditioned by comorbidity. Patients with end-stage renal failure developed with chronic kidney disease could not expect a specialty cancer treatment before the advent of long-term haemodialysis.Aim. A case description of successful perioperative therapy and surgery in a long-term haemodialysis patient performed by a multi-specialty team of oncologists and transplantologists.Materials and methods. We case-illustrate surgical treatment options in a gastric cancer patient with long-term haemodialysis.Results and discussion. A specialty oncological treatment of end-stage renal failure patients requiring long-term haemodialysis is a complex multidisciplinary task feasible in hospitals equipped for different haemodialysis regimens. The treatment plan should be laid out by a multi-specialty team, as chronic kidney disease influences the choice of the drug class, dosage and administration mode. Moreover, such patients need laboratory (control of acid-base balance, haemoglobin, electrolytes, creatinine and urea) and clinical (body weight, liquid balance, etc.) monitoring.Conclusion. Perioperative management studies in gastric cancer and chronic kidney disease-comorbid patients under long-term haemodialysis is a promising area of combining eff ort in oncology and transplantation science. Further research is needed in this topic for data enrichment and analysis in complex comorbidity patients.
慢性肾病长期血液透析患者胃恶性肿瘤的手术治疗
背景癌症是世界第五大恶性肿瘤,其治疗成功很大程度上取决于合并症。在长期血液透析出现之前,患有慢性肾脏病的终末期肾衰竭患者不可能指望得到专门的癌症治疗。目标由肿瘤学家和移植学家组成的多专业团队对一名长期血液透析患者成功进行围手术期治疗和手术的病例描述。材料和方法。我们案例说明了癌症长期血液透析患者的手术治疗方案。结果和讨论。需要长期血液透析的终末期肾衰竭患者的专业肿瘤学治疗是一项复杂的多学科任务,在配备不同血液透析方案的医院是可行的。治疗计划应由多专业团队制定,因为慢性肾脏疾病会影响药物类别、剂量和给药模式的选择。此外,这类患者需要实验室(酸碱平衡、血红蛋白、电解质、肌酐和尿素的控制)和临床(体重、液体平衡等)监测。结论癌症和慢性肾脏病合并症患者的围手术期管理研究长期血液透析是肿瘤学和移植科学中一个很有前途的联合治疗领域。需要在这一主题中进行进一步的研究,以丰富和分析复杂共病患者的数据。
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