Skin lesion, neuralgia and blood pressure before and after early formal treatment on herpes zoster of the head and face inadults: a quantitative study

中华医学美学美容杂志 Pub Date : 2019-12-15 DOI:10.3760/CMA.J.ISSN.1671-0290.2019.06.014

Jing Zhang, Wenge Fan, Ling-ling Wang, M. Wei, Jun Zhao, Xiaoyu Tao, Q. Xue

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Abstract

Objective To observe the changes of skin lesion, neuralgia and blood pressure in hypertension patients and non-hyperension patients before and after the early formal treatment on herpes zoster in the head and face. Methods Clinical data were collected from June 2015 to May 2018 in the Department of Dermatology, the First People＇s Hospital, Changshu, Jiangsu province. In 104 cases of hospitalized patients with herpes zoster, 46 cases had high blood pressure (hypertension group); 58 cases did not have high blood pressure (non-hypertension group). The skin lesion, numerical rating scale (NRS) and blood pressure changes were compared between the two groups before and after treatment. Results A total of 99 patients completed treatment; 45 cases in the hypertensive group included 25 males, 20 females, aged 35 to 71 (52.40±12.51) years; 54 cases in the non-hypertensive group included 30 males and 24 females, aged 36 to 75 (52.62±12.67) years. There was no statistically significant difference in the time of control, improving and healing of skin lesion (t=-0.457, -0.607 and 1.399, P>0.05) . There was no statistically significant difference in NRS between the two groups before treatment (t=-0.009, P=0.993 >0.05). After treatment, the NRS of both groups decreased compared with those before treatment, and the difference was statistically significant (F=151.130, 181.444, P 0.05). In the hypertension group, the rate of blood pressure increase before treatment was 62.22%, and the blood pressure decreased after treatment compared with that before treatment. The difference was statistically significant (P 0.05). Conclusions Blood pressure can be increased when herpes zoster occurs. After early formal treatment of herpes zoster, skin lesion healed, neuralgia reduced and blood pressure can return to normal. The history of hypertension and the increase of blood pressurd before treatment has no effect on the recovery of skin lesion and neuralgia. Key words: Herpes zoster; Skin manifestations; Hypertension; Neuralgia; Treatment

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头面部带状疱疹早期正规治疗前后皮肤病变、神经痛和血压的定量研究

目的观察早期正规治疗头面部带状疱疹前后高血压患者和非高血压患者的皮肤病变、神经痛和血压的变化。方法收集江苏省常熟市第一人民医院皮肤科2015年6月至2018年5月的临床资料。104例带状疱疹住院患者中，高血压46例（高血压组）；58例无高血压（非高血压组）。比较两组治疗前后的皮肤损伤、数值评定量表（NRS）和血压变化。结果共有99例患者完成治疗；高血压组45例，男25例，女20例，年龄35-71岁（52.40±12.51）岁；非高血压组54例，男30例，女24例，年龄36～75岁（52.62±12.67）岁。在控制、改善和治愈皮肤病变的时间上无统计学意义（t=-0.457、-0.607和1.399，P>0.05）。两组治疗前NRS无统计学意义差异（t=-0.009，P=0.993>0.05）。治疗后，两组NRS均较治疗前下降，高血压组治疗前血压升高率为62.22%，治疗后血压较治疗前下降。结论带状疱疹可引起血压升高。带状疱疹经早期正规治疗后，皮肤病变痊愈，神经痛减轻，血压可恢复正常。高血压病史和治疗前血压升高对皮肤病变和神经痛的恢复没有影响。关键词：带状疱疹；皮肤表现；高血压；神经痛；治疗

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来源期刊

中华医学美学美容杂志

自引率

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发文量

4641

期刊介绍： "Chinese Journal of Medical Aesthetics and Cosmetology" is a high-end academic journal focusing on the basic theoretical research and clinical application of medical aesthetics and cosmetology. In March 2002, it was included in the statistical source journals of Chinese scientific and technological papers of the Ministry of Science and Technology, and has been included in the full-text retrieval system of "China Journal Network", "Chinese Academic Journals (CD-ROM Edition)" and "China Academic Journals Comprehensive Evaluation Database". Publishes research and applications in cosmetic surgery, cosmetic dermatology, cosmetic dentistry, cosmetic internal medicine, physical cosmetology, drug cosmetology, traditional Chinese medicine cosmetology and beauty care. Columns include: clinical treatises, experimental research, medical aesthetics, experience summaries, case reports, technological innovations, reviews, lectures, etc.