Immunoagglutination Test Using Monoclonal Antibodies Coupled to Latex Particles to Identify The Streptococcus Pneumoniae Capsular Polysaccharides Serotype 1, 5, 6B, 14 And 19F In Quimi-Vio Vaccine

Abstract

Introduction: Two types of pneumococcal vaccines have been approved for use in humans. All use the capsular polysaccharide (PsC), as a vaccine antigen, conjugated or not. Quimi-Vio, the Cuban pneumococcal vaccine, is composed by seven PsC (1,5,6B,14,18C,19F,23F)all conjugated to Tetanus Toxoid. The identification of these PsCs in the vaccine formulation is a mandatory requirement for the final lots release.