Association Between Diabetic Control And Anti-Diabetic Medication Adherence Using 8-Point Morisky Medication Adherence Scale In Local Population Of Khyber Pakhtunkhwa

Journal of Rawalpindi Medical College Pub Date : 2023-06-24 DOI:10.37939/jrmc.v27i2.2249

F. A. Siddiqi, Bilal Saeed, Mehmood Hussain, Wasif Anwar, S. Riaz, Naveed Abbas

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Abstract

Abstract: Background: Drug adherence to medications in diabetes is very necessary for strict glycemic control. Many factors in diabetics are associated with low adherence to drugs resulting in complications. Methods: This research was conducted as an observational study with cross-sectional study design. It was scheduled between July 2022 to December 2022 in medical outpatient department of Combined Military Hospital, Peshawar Results: 115 individuals were inducted over a period of 6 months from medical OPD ex Combined Military Hospital Peshawar. Five patients failed to follow-up with research team resulting in a total of 110 participants included in results. Average age across the study sample was 50.25 ± 11.97 years with 58 (52.73%) males and 52 (47.27%) females. Most participant in our study sample were educated up to matriculation with BMI <25kg/m2. Average duration of diabetes across the sample was 6.1 ± 3.69 years. In treatment options, 53 (48.18%) individuals were only managed with oral therapy, 16 (14.55%) on insulin only while 41 (37.27%) were prescribed with both oral hypoglycemic drugs and insulin. Most common comorbid across study population was hypertension, seen in 59 (53.94%) diabetic patients, followed by cataract in 41 (37.47%) and IHD in 33 (30%) patients. In all 110 individuals, only 29 (26.36%) individuals had good glycemic control i.e., HbA1c <7% with average glycosylated hemoglobin percentage measuring 8.29% ± 1.59%. As per MMAS-8 score, 25 (22.73%) patients reported good adherence, 31 (28.18%) patients reported fair adherence while rest 54 (49.09%) were found to have bad adherence. Average MMAS-8 score was 5.17. Conclusion: There is a correlation between medication adherence as measured by MMAS-8 score with control of diabetes as measured by HbA1c score in the range of 1.824% across the range of MMAS-8 score from 0-8. Sleep quality, BMI and multiple comorbid conditions were also linked with raised HbA1c. Key words: Drug adherence, Morisky Medication Adherence Scale, Diabetes, Non-diabetes, diabetic medications

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开伯尔-普赫图赫瓦省当地人群糖尿病控制与抗糖尿病药物依从性的关系

摘要：背景：糖尿病患者坚持服药对于严格控制血糖是非常必要的。糖尿病患者的许多因素与药物依从性低有关，从而导致并发症。方法：本研究为观察性研究，采用横断面研究设计。计划于2022年7月至2022年12月在白沙瓦联合军事医院门诊部进行。结果：115人在6个月的时间里从白沙瓦前联合军事医院的门诊部入选。五名患者未能与研究团队进行随访，结果中共有110名参与者。研究样本的平均年龄为50.25±11.97岁，其中58名（52.73%）男性和52名（47.27%）女性。在我们的研究样本中，大多数参与者在入学前接受了BMI<25kg/m2的教育。整个样本的糖尿病平均持续时间为6.1±3.69年。在治疗方案中，53人（48.18%）仅接受口服治疗，16人（14.55%）仅接受胰岛素治疗，41人（37.27%）同时接受口服降糖药和胰岛素治疗。研究人群中最常见的合并症是高血压，59例（53.94%）糖尿病患者出现高血压，其次是白内障41例（37.47%）和IHD 33例（30%）。在所有110名患者中，只有29名（26.36%）患者血糖控制良好，即HbA1c<7%，平均糖化血红蛋白百分比为8.29%±1.59%。根据MMAS-8评分，25名（22.73%）患者报告良好依从性，31名（28.18%）患者报告尚可依从性，其余54名（49.09%）患者发现依从性差。MMAS-8平均得分为5.17。结论：通过MMAS-8评分测量的药物依从性与通过HbA1c评分测量的糖尿病控制之间存在相关性，在MMAS-8从0-8分的范围内，其范围为1.824%。睡眠质量、BMI和多种合并症也与HbA1c升高有关。关键词：药物依从性，Morisky药物依从性量表，糖尿病，非糖尿病，糖尿病药物

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Journal of Rawalpindi Medical College

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审稿时长

24 weeks