The curing regimens of HCV: A SWOT analysis

IF 1.3 4区医学 Q4 INFECTIOUS DISEASES

Antiviral Therapy Pub Date : 2022-04-01 DOI:10.1177/13596535211072672

M. Cornberg, M. Manns

引用次数: 3

Abstract

The development of direct-acting antivirals (DAA) has revolutionized the treatment of chronic hepatitis C, enabling cure of hepatitis C virus (HCV) infection in more than 95% of cases. There are essentially no contraindications, so almost any patient can now be successfully treated. The result is the prevention or amelioration of cirrhosis, hepatocellular carcinoma (HCC), and extrahepatic manifestations. Consequently, the 2020 Nobel Prize in Medicine and Physiology was awarded for the discovery of HCV. Due to the high efficacy of therapy, even global HCV elimination is conceivable even without a vaccine. Here, we would like to venture a SWOT analysis of current HCV therapies aimed at HCV elimination.

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丙型肝炎病毒治疗方案的SWOT分析

直接作用抗病毒药物（DAA）的开发彻底改变了慢性丙型肝炎的治疗，使95%以上的病例能够治愈丙型肝炎病毒（HCV）感染。基本上没有禁忌症，所以现在几乎任何患者都可以成功治疗。其结果是预防或改善肝硬化、肝细胞癌（HCC）和肝外表现。因此，2020年诺贝尔医学和生理学奖因丙型肝炎病毒的发现而获得。由于治疗的高效性，即使没有疫苗，也可以想象全球消除丙型肝炎病毒。在这里，我们想对目前旨在消除丙型肝炎病毒的丙型肝炎病毒疗法进行SWOT分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Antiviral Therapy 医学-病毒学

CiteScore

2.60

自引率

8.30%

发文量

审稿时长

4-8 weeks

期刊介绍： Antiviral Therapy (an official publication of the International Society of Antiviral Research) is an international, peer-reviewed journal devoted to publishing articles on the clinical development and use of antiviral agents and vaccines, and the treatment of all viral diseases. Antiviral Therapy is one of the leading journals in virology and infectious diseases. The journal is comprehensive, and publishes articles concerning all clinical aspects of antiviral therapy. It features editorials, original research papers, specially commissioned review articles, letters and book reviews. The journal is aimed at physicians and specialists interested in clinical and basic research.