Migraine headache in Multiple Sclerosis. Is more frequent among MS patients?

Q4 Medicine

Romanian Journal of Neurology/ Revista Romana de Neurologie Pub Date : 2023-03-31 DOI:10.37897/rjn.2023.1.9

A. Saberi, Mandana Ashkan, H. Hatamian, A. Ashraf, Enayatollah Homaie Rad, A. Bakhshi, Kasra Sarlak, Kamal AmirAshjei Asalemi, Nima Broomand Lomer

{"title":"Migraine headache in Multiple Sclerosis. Is more frequent among MS patients?","authors":"A. Saberi, Mandana Ashkan, H. Hatamian, A. Ashraf, Enayatollah Homaie Rad, A. Bakhshi, Kasra Sarlak, Kamal AmirAshjei Asalemi, Nima Broomand Lomer","doi":"10.37897/rjn.2023.1.9","DOIUrl":null,"url":null,"abstract":"Objectives. Multiple sclerosis (MS) is a chronic disease of the central nervous system that is associated with inflammation, demyelination of neurons and gliosis. There are different reports about the association between migraine and MS. Taking note of headaches experienced by people with MS and providing appropriate treatment can help enhance their quality of life. We aimed to determine the frequency of migraine headache in MS patients. Materials and methods. This was a descriptive cross-sectional study, conducted in 2020 among 125 MS patients referred to neurology clinic of Poursina Hospital or registered in Guilan MS Registry System and 125 controls with minor head trauma in Rasht. After obtaining written consent, all the subjects were asked to fulfil a checklist about their demographics, MS and headache characteristics by phone call. Outcomes. In this study 96 RRMS, 19 PPMS and 10 SPMS patients participated among which frequency of mild, moderate and severe disability was 74.4%, 22.4% and 3.2%, respectively. The frequency of migraine in MS patients was significantly higher than the control group [28.8% (n=36) vs. 12.8% (n=16) p=0.002]. After adjusting the confounding factors a significant relationship was found between MS and migraine (OR: 2.76, p = 0.004). Conclusions. MS patients experience migraine headaches approximately twice the general population.","PeriodicalId":37662,"journal":{"name":"Romanian Journal of Neurology/ Revista Romana de Neurologie","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian Journal of Neurology/ Revista Romana de Neurologie","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37897/rjn.2023.1.9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}

引用次数: 0

Abstract

Objectives. Multiple sclerosis (MS) is a chronic disease of the central nervous system that is associated with inflammation, demyelination of neurons and gliosis. There are different reports about the association between migraine and MS. Taking note of headaches experienced by people with MS and providing appropriate treatment can help enhance their quality of life. We aimed to determine the frequency of migraine headache in MS patients. Materials and methods. This was a descriptive cross-sectional study, conducted in 2020 among 125 MS patients referred to neurology clinic of Poursina Hospital or registered in Guilan MS Registry System and 125 controls with minor head trauma in Rasht. After obtaining written consent, all the subjects were asked to fulfil a checklist about their demographics, MS and headache characteristics by phone call. Outcomes. In this study 96 RRMS, 19 PPMS and 10 SPMS patients participated among which frequency of mild, moderate and severe disability was 74.4%, 22.4% and 3.2%, respectively. The frequency of migraine in MS patients was significantly higher than the control group [28.8% (n=36) vs. 12.8% (n=16) p=0.002]. After adjusting the confounding factors a significant relationship was found between MS and migraine (OR: 2.76, p = 0.004). Conclusions. MS patients experience migraine headaches approximately twice the general population.

查看原文本刊更多论文

多发性硬化症的偏头痛。是否在多发性硬化症患者中更常见?

目标。多发性硬化症（MS）是一种中枢神经系统的慢性疾病，与炎症、神经元脱髓鞘和胶质增生有关。关于偏头痛和多发性硬化症之间的关系，有不同的报道。注意多发性痴呆症患者所经历的头痛，并提供适当的治疗，有助于提高他们的生活质量。我们旨在确定多发性硬化症患者偏头痛的发生频率。材料和方法。这是一项描述性横断面研究，于2020年在125名转诊至波尔西纳医院神经科诊所或在吉兰MS登记系统登记的MS患者和125名Rasht轻度头部创伤的对照组中进行。在获得书面同意后，所有受试者都被要求通过电话填写一份关于其人口统计学、多发性硬化症和头痛特征的检查表。结果。本研究共有96例RRMS、19例PPMS和10例SPMS患者参与，其中轻度、中度和重度残疾的发生率分别为74.4%、22.4%和3.2%。多发性硬化症患者的偏头痛发生率显著高于对照组[28.8%（n=36）vs.12.8%（n=16）p=0.002]。在调整混杂因素后，发现多发性痴呆症与偏头痛之间存在显著关系（OR:2.76，p=0.004）。结论。多发性硬化症患者的偏头痛症状大约是普通人群的两倍。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Romanian Journal of Neurology/ Revista Romana de Neurologie Medicine-Neurology (clinical)

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

4 weeks

期刊介绍： ROMANIAN JOURNAL OF NEUROLOGY (Revista Română de Neurologie), the official journal of the Romanian Society of Neurology, was founded in 2001, being a prestigious scientific journal that provides a high quality in terms of scientific content, but also the editorial and graphic aspect, both through an impartial process of selection, evaluation and correction of articles (peer review procedure), as well as providing editorial, graphic and printing conditions at the highest level. In order to increase the scientific standards of the journal, special attention was paid to the improvement of the quality of the published materials. Guidance articles, clinical trials and case studies are structured in several sections: reviews, original articles, case reports, images in neurology. All articles are published entirely in English. A team of reputable medical professionals in the field of neurology is involved in a rigorous peer review process that complies with international ethics and quality rules in the academic world.