An Approach to Early Diagnosis of Pneumonia on Individual Radiographs based on the CNN Information Technology

Q3 Computer Science
Pavlo Radiuk, O. Barmak, I. Krak
{"title":"An Approach to Early Diagnosis of Pneumonia on Individual Radiographs based on the CNN Information Technology","authors":"Pavlo Radiuk, O. Barmak, I. Krak","doi":"10.2174/1875036202114010093","DOIUrl":null,"url":null,"abstract":"\n \n This study investigates the topology of convolutional neural networks and proposes an information technology for the early detection of pneumonia in X-rays.\n \n \n \n For the past decade, pneumonia has been one of the most widespread respiratory diseases. Every year, a significant part of the world's population suffers from pneumonia, which leads to millions of deaths worldwide. Inflammation occurs rapidly and usually proceeds in severe forms. Thus, early detection of the disease plays a critical role in its successful treatment.\n \n \n \n The most operating means of diagnosing pneumonia is the chest X-ray, which produces radiographs. Automated diagnostics using computing devices and computer vision techniques have become beneficial in X-ray image analysis, serving as an ancillary decision-making system. Nonetheless, such systems require continuous improvement for individual patient adjustment to ensure a successful, timely diagnosis.\n \n \n \n Nowadays, artificial neural networks serve as a promising solution for identifying pneumonia in radiographs. Despite the high level of recognition accuracy, neural networks have been perceived as black boxes because of the unclear interpretation of their performance results. Altogether, an insufficient explanation for the early diagnosis can be perceived as a severe negative feature of automated decision-making systems, as the lack of interpretation results may negatively affect the final clinical decision. To address this issue, we propose an approach to the automated diagnosis of early pneumonia, based on the classification of radiographs with weakly expressed disease features.\n \n \n \n An effective spatial convolution operation with several dilated rates, combining various receptive feature fields, was used in convolutional layers to detect and analyze visual deviations in the X-ray image. Due to applying the dilated convolution operation, the network avoids significant losses of objects' spatial information providing relatively low computational costs. We also used transfer training to overcome the lack of data in the early diagnosis of pneumonia. An image analysis strategy based on class activation maps was used to interpret the classification results, critical for clinical decision making.\n \n \n \n According to the computational results, the proposed convolutional architecture may be an excellent solution for instant diagnosis in case of the first suspicion of early pneumonia.\n","PeriodicalId":38956,"journal":{"name":"Open Bioinformatics Journal","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-11-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Bioinformatics Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1875036202114010093","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Computer Science","Score":null,"Total":0}
引用次数: 3

Abstract

This study investigates the topology of convolutional neural networks and proposes an information technology for the early detection of pneumonia in X-rays. For the past decade, pneumonia has been one of the most widespread respiratory diseases. Every year, a significant part of the world's population suffers from pneumonia, which leads to millions of deaths worldwide. Inflammation occurs rapidly and usually proceeds in severe forms. Thus, early detection of the disease plays a critical role in its successful treatment. The most operating means of diagnosing pneumonia is the chest X-ray, which produces radiographs. Automated diagnostics using computing devices and computer vision techniques have become beneficial in X-ray image analysis, serving as an ancillary decision-making system. Nonetheless, such systems require continuous improvement for individual patient adjustment to ensure a successful, timely diagnosis. Nowadays, artificial neural networks serve as a promising solution for identifying pneumonia in radiographs. Despite the high level of recognition accuracy, neural networks have been perceived as black boxes because of the unclear interpretation of their performance results. Altogether, an insufficient explanation for the early diagnosis can be perceived as a severe negative feature of automated decision-making systems, as the lack of interpretation results may negatively affect the final clinical decision. To address this issue, we propose an approach to the automated diagnosis of early pneumonia, based on the classification of radiographs with weakly expressed disease features. An effective spatial convolution operation with several dilated rates, combining various receptive feature fields, was used in convolutional layers to detect and analyze visual deviations in the X-ray image. Due to applying the dilated convolution operation, the network avoids significant losses of objects' spatial information providing relatively low computational costs. We also used transfer training to overcome the lack of data in the early diagnosis of pneumonia. An image analysis strategy based on class activation maps was used to interpret the classification results, critical for clinical decision making. According to the computational results, the proposed convolutional architecture may be an excellent solution for instant diagnosis in case of the first suspicion of early pneumonia.
基于CNN信息技术的个体x线片肺炎早期诊断方法
本研究探讨了卷积神经网络的拓扑结构,并提出了一种在x射线中早期检测肺炎的信息技术。在过去十年中,肺炎一直是传播最广泛的呼吸道疾病之一。每年,世界上很大一部分人口患有肺炎,导致全世界数百万人死亡。炎症发生迅速,通常以严重的形式发展。因此,疾病的早期发现对其成功治疗起着关键作用。诊断肺炎最常用的方法是胸部x光片,它能产生x光片。使用计算机设备和计算机视觉技术的自动诊断在x射线图像分析中已经成为有益的,作为辅助决策系统。尽管如此,这样的系统需要不断改进个体患者的调整,以确保成功,及时的诊断。如今,人工神经网络作为一种很有前途的解决方案,可以在x光片中识别肺炎。尽管神经网络的识别精度很高,但由于对其性能结果的解释不明确,神经网络一直被视为黑盒子。总之,对早期诊断的解释不足可以被视为自动决策系统的一个严重的负面特征,因为缺乏解释结果可能会对最终的临床决策产生负面影响。为了解决这个问题,我们提出了一种基于弱表达疾病特征的x线片分类的早期肺炎自动诊断方法。在卷积层中,结合不同的接收特征场,采用几种扩展率的有效空间卷积运算来检测和分析x射线图像中的视觉偏差。由于采用了扩展卷积运算,网络避免了物体空间信息的大量丢失,并且计算成本相对较低。我们还使用转移训练来克服肺炎早期诊断数据的缺乏。使用基于类激活图的图像分析策略来解释分类结果,这对临床决策至关重要。计算结果表明,在首次怀疑早期肺炎的情况下,所提出的卷积架构可能是一种极好的即时诊断方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Open Bioinformatics Journal
Open Bioinformatics Journal Computer Science-Computer Science (miscellaneous)
CiteScore
2.40
自引率
0.00%
发文量
4
期刊介绍: The Open Bioinformatics Journal is an Open Access online journal, which publishes research articles, reviews/mini-reviews, letters, clinical trial studies and guest edited single topic issues in all areas of bioinformatics and computational biology. The coverage includes biomedicine, focusing on large data acquisition, analysis and curation, computational and statistical methods for the modeling and analysis of biological data, and descriptions of new algorithms and databases. The Open Bioinformatics Journal, a peer reviewed journal, is an important and reliable source of current information on the developments in the field. The emphasis will be on publishing quality articles rapidly and freely available worldwide.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信