Tuberculosis for Alzheimer’s: Risk Factor, Treatment or Prevention

A. Yaghoubi, K. Ghazvini, S. Hashemy
{"title":"Tuberculosis for Alzheimer’s: Risk Factor, Treatment or Prevention","authors":"A. Yaghoubi, K. Ghazvini, S. Hashemy","doi":"10.22038/RCM.2020.46969.1310","DOIUrl":null,"url":null,"abstract":"Alzheimer's disease is a type of dementia and there were 50 million individuals have dementia in 2018 worldwide and the cost of dementia care to Medicare and Medicaid is so high (about US$1 trillion) in that year. Recently, several articles show that tuberculosis may be increased the development rate of Alzheimer's disease in these patients. So knowing the probable relationship between these two could be helpful. Also, there is evidence demonstrating that the Bacillus Calmette–Guerin (BCG) vaccine and rifampicin as a conventional vaccine and medicine against Mycobacterium tuberculosis infections could be used as a promising agent for the prevention and reduce the development of Alzheimer’s disease and other neurodegenerative diseases. According to our knowledge, the present review is the first and only review that assessed the possible relationship between tuberculosis and Alzheimer's disease as well as the possible therapeutic role of rifampicin and BCG vaccine in treatment and prevention of Alzheimer's disease, respectively.","PeriodicalId":21081,"journal":{"name":"Reviews in Clinical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reviews in Clinical Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22038/RCM.2020.46969.1310","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Alzheimer's disease is a type of dementia and there were 50 million individuals have dementia in 2018 worldwide and the cost of dementia care to Medicare and Medicaid is so high (about US$1 trillion) in that year. Recently, several articles show that tuberculosis may be increased the development rate of Alzheimer's disease in these patients. So knowing the probable relationship between these two could be helpful. Also, there is evidence demonstrating that the Bacillus Calmette–Guerin (BCG) vaccine and rifampicin as a conventional vaccine and medicine against Mycobacterium tuberculosis infections could be used as a promising agent for the prevention and reduce the development of Alzheimer’s disease and other neurodegenerative diseases. According to our knowledge, the present review is the first and only review that assessed the possible relationship between tuberculosis and Alzheimer's disease as well as the possible therapeutic role of rifampicin and BCG vaccine in treatment and prevention of Alzheimer's disease, respectively.
结核病对阿尔茨海默病:危险因素,治疗或预防
阿尔茨海默病是一种痴呆症,2018年全球有5000万人患有痴呆症,当年医疗保险和医疗补助的痴呆症护理费用非常高(约1万亿美元)。最近,几篇文章表明,结核病可能会增加这些患者阿尔茨海默病的发展速度。因此,了解这两者之间的可能关系可能会有所帮助。此外,有证据表明,卡介苗和利福平作为抗结核分枝杆菌感染的常规疫苗和药物,可以作为预防和减少阿尔茨海默病和其他神经退行性疾病发展的有希望的药物。据我们所知,本综述是第一篇也是唯一一篇评估结核病与阿尔茨海默病之间可能的关系以及利福平和卡介苗分别在治疗和预防阿尔茨海默病方面可能发挥的治疗作用的综述。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
审稿时长
24 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信