{"title":"Impact of cadmium pollution on food safety and human health","authors":"Ibha Suhani, Sinha Sahab, Vaibhav Srivastava, Rajeev Pratap Singh","doi":"10.1016/j.cotox.2021.04.004","DOIUrl":null,"url":null,"abstract":"<div><p><span>Owing to modern-day urbanization and industrial activities, heavy metal pollution and its environmental impact have drawn the attention of the scientific community towards itself. Among all the heavy metals, cadmium is known to have no biological function, and its presence harms almost all life forms. Cadmium (Cd) has natural and anthropogenic sources of entry into the ecosystem. It is nonbiodegradable and is present in different trophic levels in the food chain, raising concern over food safety. The bioavailability, bioaccessibility, and accumulation of Cd in soil-plant systems are the main drivers of its transfer to different trophic levels via diverse routes. In the human system, bioaccumulation of Cd disrupts the antioxidant defense system due to induced </span>oxidative stress<span> as a result of reactive oxygen species generation, which further causes different ailments. This review provides an update on the effects of Cd exposure on the soil-plant system, food safety, and human health, focusing on the various mechanisms involved in cellular or molecular alterations.</span></p></div>","PeriodicalId":37736,"journal":{"name":"Current Opinion in Toxicology","volume":"27 ","pages":"Pages 1-7"},"PeriodicalIF":6.1000,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.cotox.2021.04.004","citationCount":"102","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Opinion in Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2468202021000176","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"TOXICOLOGY","Score":null,"Total":0}
引用次数: 102
Abstract
Owing to modern-day urbanization and industrial activities, heavy metal pollution and its environmental impact have drawn the attention of the scientific community towards itself. Among all the heavy metals, cadmium is known to have no biological function, and its presence harms almost all life forms. Cadmium (Cd) has natural and anthropogenic sources of entry into the ecosystem. It is nonbiodegradable and is present in different trophic levels in the food chain, raising concern over food safety. The bioavailability, bioaccessibility, and accumulation of Cd in soil-plant systems are the main drivers of its transfer to different trophic levels via diverse routes. In the human system, bioaccumulation of Cd disrupts the antioxidant defense system due to induced oxidative stress as a result of reactive oxygen species generation, which further causes different ailments. This review provides an update on the effects of Cd exposure on the soil-plant system, food safety, and human health, focusing on the various mechanisms involved in cellular or molecular alterations.
期刊介绍：
The aims and scope of Current Opinion in Toxicology is to systematically provide the reader with timely and provocative views and opinions of the highest qualified and recognized experts on current advances in selected topics within the field of toxicology. The goal is that Current Opinion in Toxicology will be an invaluable source of information and perspective for researchers, teachers, managers and administrators, policy makers and students. Division of the subject into sections: For this purpose, the scope of Toxicology is divided into six selected high impact themed sections, each of which is reviewed once a year: Mechanistic Toxicology, Metabolic Toxicology, Risk assessment in Toxicology, Genomic Toxicology, Systems Toxicology, Translational Toxicology.
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