Gene Associated And Risk Factor Of HPV Wharts: A Review Article

Abstract

Introduction: HPV can infect basal epithelial cells of the skin or deep tissue and are categorized as either skin type or mucosal type. This skin type is epidermotropic and infects the surface of the keratinized skin, targeting the skin of the hands and feet. The type of mucosa that is infected is the lining of the mouth, throat, respiratory, or anogenital as 28 types that have been identified so far can use various methods. Identification of viral DNA or RNA by various hybridization techniques. Time to analyze the results is also very important to know the validity of the different HPV techniques, the sensitivity, specificity, and the spectrum of HPV types detected. Southern Blot hybridization is still used as the standard for DNA identification of various types of HPV. However, between 5000 and 50 000 copies of HPV DNA must be present in a clinical sample to be detected [4]. In addition to VLP, HPV DNA is also most common in women under 25 years of age prevalence tends to peak in women over 25 years of age using HPV antibodies. Number of sexual partners was recognized as an independent risk factor for genital HPV infection in patients with immunosuppression will also be a risk factor for HPV infection, for example in patients with autoimmune, HIV infection and organ transplantation in patients with autoimmune, HIV and organ transplantation. Serological tests for certain types of HPV have been used to detect antibodies to viral particles such as (VLP), which is a viral capsid synthesized from the viral L1 protein. The prevalence of HPV infection using VLP as antigen showed that, among women clinically absent of HPV, 2-43% had antibodies to HPV 16, and 9-25% had antibodies to HPV 6 or 11. The seroprevalence of other types, including 18, 31, 33, 39, 58, and 59, ranging from 9% to 23%. In addition to VLP, HPV DNA is also most common in women under 25 years of age, prevalence tends to peak in women over 25 years of age using HPV antibodies The study 21% of = 90) reported having only one male sexual partner positive PCR method compared with 69% Frequently changing partners more Previous studies have not shown an association between HPV detection and sexual activity, due to the possibility of misclassifying HPV and its manifestations and the small sample size of subjects may distort the results. Subclinical HPV infection and HPV-associated disease common (64% male HPV intraepithelial