Maternal and Neonatal Outcomes in Pregnant Women With COVID-19 Admitted to Imam Khomeini Hospital of Sari, Iran, 2019 - 2020

IF 0.5 Q4 INFECTIOUS DISEASES

Archives of Clinical Infectious Diseases Pub Date : 2023-04-05 DOI:10.5812/archcid-119394

Marzieh Zamaniyan, Z. Rahmani, R. Ghasemian, Z. Karimi, Roghaye-Khatoon Arab, A. Ebadi, S. Moradi, Shabnam Sharjerdi, Samaneh Aghajanpour Mir, Setareh Azizi

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引用次数: 0

Abstract

Background: The COVID-19 infection may adversely affect both the mother and baby. Evaluation and identification of aggravating factors can help prevent adverse outcomes. Objectives: The present study aimed to examine pregnant women with COVID-19 infection and evaluate the disease outcomes in Sari, Iran. Methods: The present case series study was performed on 17 pregnant women hospitalized for COVID-19 in Sari. A convenience sampling method was used. First, the researcher took the demographic information and medical history and obtained informed consent from all participants. Then, the selected subjects were examined for inclusion and exclusion criteria, and a throat swab sample was taken from eligible ones for PCR. The PCR was performed for amniotic fluid and neonatal throat samples at pregnancy termination. Six weeks after delivery, the status of rehospitalization of the baby, breastfeeding status, rehospitalization of the mother due to COVID-19, and the state of depression of the mother were evaluated by a 21-item questionnaire over the phone. The collected data were analyzed in SPSS version 23 using the Chi-square test. Results: Out of 19 participants, 17 (68%) had positive results for COVID-19 laboratory tests. The prevalence of preterm labor, admission to the neonatal intensive care unit, and vertical transmission were significantly high in pregnant women with COVID-19 and positive PCR results for amniotic fluid (P < 0.050). The frequency of admission to the ICU was significantly higher in pregnant women with diabetes infected with COVID-19 (P = 0.025). There was no rehospitalization of the mother and newborn due to COVID-19, but one case of postpartum depression (9.5%) and two cases of formula feeding (11.8%) were reported. Conclusions: Due to the high risk of maternal and neonatal outcomes of COVID-19 during pregnancy and the high probability of vertical transmission, it is recommended to take special precautions to prevent the disease during this period.

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2019年至2020年入住伊朗萨里伊玛目霍梅尼医院的新冠肺炎孕妇的产妇和新生儿结局

背景：新冠肺炎感染可能会对母亲和婴儿产生不利影响。评估和识别加重因素有助于预防不良后果。目的：本研究旨在检查伊朗萨里感染新冠肺炎的孕妇，并评估其疾病结果。方法：对因新冠肺炎在萨里住院的17例孕妇进行病例系列研究。采用了一种方便的抽样方法。首先，研究人员获取了人口统计信息和病史，并获得了所有参与者的知情同意。然后，对所选受试者进行纳入和排除标准检查，并从符合条件的受试者中抽取咽拭子样本进行PCR。在终止妊娠时对羊水和新生儿喉咙样本进行聚合酶链式反应。产后6周，通过电话对婴儿的再住院状态、母乳喂养状态、母亲因新冠肺炎的再住院情况以及母亲的抑郁状态进行了21项问卷评估。收集的数据在SPSS 23版中使用卡方检验进行分析。结果：在19名参与者中，17人（68%）的新冠肺炎实验室检测结果呈阳性。早产的发生率，新生儿重症监护室的入院率，新冠肺炎孕妇和羊水PCR阳性孕妇的垂直传播率显著较高（P＜0.050）。新冠肺炎糖尿病孕妇入住ICU的频率明显较高（P＝0.025），产后抑郁症1例（9.5%），配方奶粉喂养2例（11.8%）。结论：由于新冠肺炎在妊娠期间的产妇和新生儿结局风险高，垂直传播的可能性高，建议在此期间采取特殊预防措施预防疾病。

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来源期刊

Archives of Clinical Infectious Diseases INFECTIOUS DISEASES-

CiteScore

3.40

自引率

0.00%

发文量

期刊介绍： Archives of Clinical Infectious Diseases is a peer-reviewed multi-disciplinary medical publication, scheduled to appear quarterly serving as a means for scientific information exchange in the international medical forum. The journal particularly welcomes contributions relevant to the Middle-East region and publishes biomedical experiences and clinical investigations on prevalent infectious diseases in the region as well as analysis of factors that may modulate the incidence, course, and management of infectious diseases and pertinent medical problems in the Middle East.