Calciphylaxis Or Calcific Uremic Arteriolopathy: Diagnosis Not To Be Overlooked In Hemodialysis Patients

Abstract

TP 39%. An inflam matory syndrome with a CRP at 230 mg/l, a fibrinogen at 7g/l and a ferritinemia 400μg/l. phosphoremia Ca×P 6808mg²/dl²; parathormone 1-84 591pg/ml. The rereading of the biopsy reveals an infiltration of the of the and medium-sized by calcium deposits by and Von Kossa indicating the stopping of immu nosuppressants and AVK with regular skin care and daily dialysis by calcium concentration 1.25mmol/l. Abstract Calciphylaxis or calcific uremic arteriolopathy is a rare and se - vere condition due to its painful ischemic necrosis cutaneous and sometimes systemic lesions, whose functional and vital prognosis is reserved due to infectious complications. Several factors are impli -cated, but the physiopathology is not yet fully understood. Its treat - ment is poorly codified based mainly on a treatment of pain, tissue oxygenation, the release of calcium salts of vessels and the elimina - tion of factors and promoting drugs. We illustrate through a clinical case the essential points to recognize on this pathology.