Comparison between cardiovascular effects of adrenaline and phenylephrine associated with lidocaine and the effects of felypressin with prilocaine during intrabucal anesthesia in ASA I patients

Q4 Dentistry

Revista Odonto Ciencia Pub Date : 2018-12-30 DOI:10.15448/1980-6523.2018.1.29848

Tatiany Bertollo Cozer Ribeiro Da Costa, A. M. Cabral, R. P. Cançado

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引用次数: 0

Abstract

OBJECTIVE: Evaluate the cardiovascular effects by infiltration of 1:100.000 epinephrine and 1:2.500 phenylephrine associated with 2% lidocaine compared with the effects by infiltration of 0.03 IU/ml felypressin with 3% prilocaine, during surgery of third molars in ASA I patients.METHODS: Eighteen patients were divided into two groups. In group I (GI), the effects of epinephrine vs felypressin were evaluated and in group II (GII), the effects of phenylephrine vs felypressin. Cardiovascular parameters: systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR) and oxygen saturation (SatO2) were measured in pre, trans and post-operative periods.RESULTS: Statistical analysis (T-TEST) on the cardiovascular parameters demonstrated with significance that, GI: felypressin presented HR average reduction in the postoperative period and SatO2 average reduction in trans and postoperative periods. For GII: felypressin presented SatO2 average reduction in the postoperative period; SBP averages for patients submitted to phenylephrine increased in trans and postoperative periods; and DBP averages for patients submitted to phenylephrine increased in pre and trans-operative periods.COCLUSION: We can conclude that phenylephrine may lead to increased SBP and DBP and felypressin generated a reduction in HR and SatO2. All these changes were well tolerated by ASA I patients.

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肾上腺素、苯肾上腺素联合利多卡因对心血管的影响及氟利加压素联合普利卡因对ASA I型患者腋内麻醉的影响

目的：在ASA I患者的第三磨牙手术中，评估1∶100.000肾上腺素和1∶2.500苯肾上腺素与2%利多卡因联合渗透对心血管的影响，并与0.03 IU/ml非加压素与3%普洛卡因联合渗透的影响进行比较。方法：将18例患者分为两组。在第一组（GI）中，评估肾上腺素与非加压素的作用，在第二组（GII）中，评价苯肾上腺素与非压迫素的作用。心血管参数：在术前、术中和术后测量收缩压（SBP）、舒张压（DBP）、心率（HR）和血氧饱和度（SatO2）。结果：对心血管参数的统计分析（T-TEST）表明，GI：非加压素在术后HR平均降低，SatO2平均降低。对于GII：在术后阶段，felypressin的SatO2平均降低；接受苯肾上腺素治疗的患者的SBP平均值在转运期和术后增加；接受苯肾上腺素治疗的患者的DBP平均值在术前和术后增加。结论：我们可以得出结论，苯肾上腺素可能导致SBP和DBP增加，而非加压素可降低HR和SatO2。ASA I患者对所有这些变化均具有良好的耐受性。

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来源期刊

Revista Odonto Ciencia Dentistry-Dentistry (all)

CiteScore

0.30

自引率

0.00%

发文量

期刊介绍： Cessation. The Revista Odonto Ciência is a peer-reviewed journal published online (ISSN 1980-6523), four times per year, supported by the Pontifical Catholic University of Rio Grande do Sul – Dental School since 1986. Its abbreviation is Rev Odonto Cienc, which should be used in references, bibliographic legends, and footnotes. The Revista Odonto Ciência is an international scientific journal dedicated to provide a forum for academics, researchers, and practitioners to communicate relevant basic, clinical, education, and epidemiological studies in Dentistry and related fields. The Journal seeks to publish articles on new conceptual models, innovative technology, alternative procedures or treatment to reduce disease burden in the general population or specific groups, thus contributing to translating science into practice and social development. Contributions falling into the following categories will be considered for publication: 1) original research reports of basic and applied oral sciences, epidemiological, and education studies; 2) review article; 3) case report. The Revista Odonto Ciência only accepts manuscripts written in English. Manuscripts submitted to this journal should not have been published before nor have publication pending elsewhere.