Hui Xie, Li Li, S. Richard, Zhigang Lan, Yuekang Zhang
{"title":"Cerebellopontine angle metastatic melanoma mimicking schwannoma in a sexagenarian: Case report","authors":"Hui Xie, Li Li, S. Richard, Zhigang Lan, Yuekang Zhang","doi":"10.7575/aiac.abcmed.v.10n.1p.33","DOIUrl":null,"url":null,"abstract":"Introduction: Metastasis of melanomas to the cerebellopontine angle (CPA) are very rare. Dissemination via blood, cerebrospinal fluid and/or leptomeninges may be the principal pathway for metastatic spread of malignant melanomas to the CPA. Case presentation: A 68-years old man presented with two years history of hearing lost in the right ear with associated dizziness and headaches. A skin lesion was seen on the patient’s right forearm. MRI revealed a nodular abnormal signal intensity at the right CPA which was resected and pathology revealed metastatic melanoma. Conclusion: Aggressive treatment regime comprising of a combination of surgery, chemotherapy and radiotherapy is very efficacious in prolonging the survival of patients with metastatic melanomas to the brain especially the metastasis to the CPA.","PeriodicalId":92322,"journal":{"name":"Advances in bioscience and clinical medicine","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advances in bioscience and clinical medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7575/aiac.abcmed.v.10n.1p.33","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Introduction: Metastasis of melanomas to the cerebellopontine angle (CPA) are very rare. Dissemination via blood, cerebrospinal fluid and/or leptomeninges may be the principal pathway for metastatic spread of malignant melanomas to the CPA. Case presentation: A 68-years old man presented with two years history of hearing lost in the right ear with associated dizziness and headaches. A skin lesion was seen on the patient’s right forearm. MRI revealed a nodular abnormal signal intensity at the right CPA which was resected and pathology revealed metastatic melanoma. Conclusion: Aggressive treatment regime comprising of a combination of surgery, chemotherapy and radiotherapy is very efficacious in prolonging the survival of patients with metastatic melanomas to the brain especially the metastasis to the CPA.