Cerebellopontine angle metastatic melanoma mimicking schwannoma in a sexagenarian: Case report

Hui Xie, Li Li, S. Richard, Zhigang Lan, Yuekang Zhang
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Abstract

Introduction: Metastasis of melanomas to the cerebellopontine angle (CPA) are very rare. Dissemination via blood, cerebrospinal fluid and/or leptomeninges may be the principal pathway for metastatic spread of malignant melanomas to the CPA. Case presentation: A 68-years old man presented with two years history of hearing lost in the right ear with associated dizziness and headaches. A skin lesion was seen on the patient’s right forearm. MRI revealed a nodular abnormal signal intensity at the right CPA which was resected and pathology revealed metastatic melanoma. Conclusion: Aggressive treatment regime comprising of a combination of surgery, chemotherapy and radiotherapy is very efficacious in prolonging the survival of patients with metastatic melanomas to the brain especially the metastasis to the CPA.
60岁老人脑桥小脑角转移性黑色素瘤模拟神经鞘瘤病例报告
引言:黑色素瘤转移到桥小脑角(CPA)是非常罕见的。通过血液、脑脊液和/或软脑膜传播可能是恶性黑色素瘤转移至CPA的主要途径。病例介绍:一名68岁的男性,有两年右耳听力损失史,伴有头晕和头痛。患者右前臂有皮肤损伤。MRI显示右侧CPA有结节性异常信号强度,切除后病理显示转移性黑色素瘤。结论:手术、化疗和放疗相结合的积极治疗方案在延长脑转移性黑色素瘤患者的生存期,尤其是CPA转移患者的生存率方面非常有效。
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