Blood Glucose and Glycogen Levels as Indicators of Stress in the Freshwater Fish, Cirrihinus mrigal under Cyphenothrin Intoxication

Q4 Pharmacology, Toxicology and Pharmaceutics
Sapna S. Anigol, Srinivas B Neglur, M. David
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引用次数: 0

Abstract

Pesticides are non-biodegradable substances used to control bugs, weeds, snails, and plant diseases. They are widely utilised in forestry, farming, and veterinary practices and are of incredible general well-being significance. Pesticides can be ordered by their utilisation into three significant sorts (in particular insect sprays, herbicides, and fungicides). Water defilement by these pesticides is known to prompt harmful effects on the creation, proliferation, and survivability of aquatic life forms, like green growth, amphibian plants, and fish (shellfish and finfish species). The information presented in this study is used to assess the negative effects of exposing fish species to pesticide concentrations. Pyrethroids are regularly utilised around the home and in agricultural production to control bugs. Human contact with at least one pyrethroid bug spray is reasonable. These synthetic substances cause serious harm to aquatic biological systems, particularly fish. The principle points and objective of the present investigation are to assess the effect of cyphenothrin on carbohydrate metabolism in the fish. Cirrihinus mrigal is a monetarily significant Indian major carp. A freshwater fish, Cirrihinus mrigal, was exposed to bug spray, i.e., cyphenothrin a manufactured pyrethroid. The LC50 for cyphenothrin at 96 hrs was 6 μg/L by probit analysis. One-fifth of LC50 (120 μg/L), was chosen as the sublethal focus. The fish were subjected to sub-lethal concentrations for 10, 20, 30 and 40 days, and the changes in starch digestion, for example, absolute glycogen, as well as the activities of catalysts Lactate Dehydrogenase (LDH) and Succinate Dehydrogenase (SDH) in critical organs, such as the gill, kidney, and liver, were studied.
氯氰菊酯中毒淡水鱼血糖和糖原水平作为应激指标的研究
农药是一种不可生物降解的物质,用于控制昆虫、杂草、蜗牛和植物病害。它们被广泛应用于林业、农业和兽医实践,具有令人难以置信的总体福祉意义。农药可按其用途分为三大类(特别是杀虫剂、除草剂和杀菌剂)。众所周知,这些农药对水的污染会对水生生物的产生、繁殖和生存能力产生有害影响,比如绿色植物、两栖植物和鱼类(贝类和鱼类)。本研究提供的信息用于评估将鱼类暴露于杀虫剂浓度的负面影响。拟除虫菊酯类杀虫剂经常在家庭周围和农业生产中使用,以控制虫子。人类至少接触一种拟除虫菊酯杀虫剂是合理的。这些合成物质对水生生物系统,特别是鱼类造成严重危害。本研究的主要目的是评价氯氰菊酯对鱼类碳水化合物代谢的影响。Cirrihinus mrigal是一种重要的印度鲤鱼。将一种淡水鱼(Cirrihinus mrigal)暴露于杀虫剂,即氯氰菊酯(一种人造拟除虫菊酯)。经probit分析,氯氰菊酯96 h的LC50为6 μg/L。取五分之一LC50 (120 μg/L)作为亚致死灶。分别在亚致死浓度下处理10、20、30和40天,研究鱼的淀粉消化(如绝对糖原)以及鳃、肾和肝等关键器官中乳酸脱氢酶(LDH)和琥珀酸脱氢酶(SDH)的活性变化。
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来源期刊
Toxicology International
Toxicology International Environmental Science-Health, Toxicology and Mutagenesis
CiteScore
0.60
自引率
0.00%
发文量
23
期刊介绍: Toxicology International is a peer-reviewed International Research Journal published bi-annually by the Society of Toxicology, India. The Journal is concerned with various disciplines of Toxicology including man, animals, plants and environment and publishes research, review and general articles besides opinions, comments, news-highlights and letters to editor.
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