G. Yıldız, F. Selvi, C. Bedel, Ökkeş Zortuk, M. Korkut, U. Mutlucan
{"title":"Systemic inflammation response index and systemic immune inflammation index for predicting acute cholecystitis","authors":"G. Yıldız, F. Selvi, C. Bedel, Ökkeş Zortuk, M. Korkut, U. Mutlucan","doi":"10.4103/injms.injms_5_23","DOIUrl":null,"url":null,"abstract":"Objective: Acute cholecystitis (AC) is a condition caused by acute inflammation of gallbladder. Many inflammatory markers are frequently used in the diagnostic process. In this study, we wanted to show the diagnostic efficacy of the systemic inflammatory response index (SIRI) and systemic immune inflammation index (SII) in patients with AC. Methods: This retrospective study was conducted in subjects diagnosed with AC between January 1, 2020, and June 1, 2022. The control group was randomly selected from subjects who attended to the emergency department with abdominal pain and did not need hospitalization, among subjects of similar age and gender to our study group. Demographic data and laboratory parameters of the patients were collected. Results: One hundred and thirty-three AC patients who met the inclusion criteria were included. Eighty-five patients with similar demographic data were included as a control group. The mean median SIRI levels of the patients were significantly higher than the control group (2.88 vs. 1.35; P < 0.001). In addition, the median SII levels of the patients were found to be significantly higher than the control group (1019.42 vs. 573.80; P < 0.001). Conclusions: We found that SIRI and SII are markers that can be used diagnostically in patients with AC and can be used as an option to C-reactive protein.","PeriodicalId":43811,"journal":{"name":"Indian Journal of Medical Specialities","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Medical Specialities","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/injms.injms_5_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: Acute cholecystitis (AC) is a condition caused by acute inflammation of gallbladder. Many inflammatory markers are frequently used in the diagnostic process. In this study, we wanted to show the diagnostic efficacy of the systemic inflammatory response index (SIRI) and systemic immune inflammation index (SII) in patients with AC. Methods: This retrospective study was conducted in subjects diagnosed with AC between January 1, 2020, and June 1, 2022. The control group was randomly selected from subjects who attended to the emergency department with abdominal pain and did not need hospitalization, among subjects of similar age and gender to our study group. Demographic data and laboratory parameters of the patients were collected. Results: One hundred and thirty-three AC patients who met the inclusion criteria were included. Eighty-five patients with similar demographic data were included as a control group. The mean median SIRI levels of the patients were significantly higher than the control group (2.88 vs. 1.35; P < 0.001). In addition, the median SII levels of the patients were found to be significantly higher than the control group (1019.42 vs. 573.80; P < 0.001). Conclusions: We found that SIRI and SII are markers that can be used diagnostically in patients with AC and can be used as an option to C-reactive protein.
目的:急性胆囊炎是一种由胆囊急性炎症引起的疾病。在诊断过程中经常使用许多炎症标志物。在本研究中,我们希望展示全身炎症反应指数(SIRI)和全身免疫炎症指数(SII)对AC患者的诊断效果。方法:本回顾性研究在2020年1月1日至2022年6月1日期间诊断为AC的受试者中进行。对照组随机选择在与本研究组年龄、性别相近的就诊于急诊科且不需要住院治疗的腹痛患者。收集患者的人口学资料和实验室参数。结果:133例AC患者符合纳入标准。85例人口统计学资料相似的患者作为对照组。患者的SIRI平均中位水平显著高于对照组(2.88 vs 1.35;P < 0.001)。此外,发现患者的SII中位数水平显著高于对照组(1019.42 vs 573.80;P < 0.001)。结论:我们发现SIRI和SII是可用于AC患者诊断的标记物,可作为c反应蛋白的一种选择。
期刊介绍:
The Indian Journal of Medical Specialities is an all-encompassing peer-reviewed quarterly journal. The journal publishes scholarly articles, reviews, case reports and original research papers from medical specialities specially pertaining to clinical patterns and epidemiological profile of diseases. An important highlight is the emphasis on undergraduate and postgraduate medical education including various aspects of scientific paper-writing. The journal gives priority to research originating from the developing world, including from the tropical regions of the world. The journal also publishes special issues on health topics of current interest. The Indian Journal of Medical Specialities is one of the very few quality multispeciality scientific medical journals.