Impact of Intra-Articular Corticosteroid Injection on Glycemic Control: A Population-Based Cohort Study.

Q2 Medicine
Clinical Diabetes Pub Date : 2024-01-01 Epub Date: 2023-08-25 DOI:10.2337/cd22-0124
Terin T Sytsma, Laura S Greenlund, Karen M Fischer, Rozalina G McCoy
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引用次数: 0

Abstract

This retrospective cohort study investigated the longer-term hyperglycemic effects of intra-articular corticosteroid (IACS) administration by evaluating changes in A1C after large joint IACS injection. Among 1,169 patients (mean age 66.1 ± 12.2 years, 52.8% female), 184 (15.7%) experienced a greater-than-expected rise in A1C (actual A1C ≥0.5% above predicted) after IACS. Greater-than-expected rise in A1C was associated solely with baseline A1C (odds ratio [OR] 1.84, 95% CI 1.08-3.13 for baseline A1C of 7.0-8.0% compared with <7.0% and OR 4.79, 95% CI 2.83-8.14 for baseline A1C >8.0% compared with <7.0%). Although most patients do not experience an increase in A1C after IACS, clinicians should counsel patients with suboptimally controlled diabetes about risks of further hyperglycemia after IACS administration.

关节内皮质类固醇注射对血糖控制的影响:一项基于人群的队列研究
这项回顾性队列研究通过评估大关节IACS注射后A1C的变化,调查了关节内皮质类固醇(IACS)给药的长期高血糖影响。在1169名患者(平均年龄66.1±12.2岁)中,52.8%为女性),184名(15.7%)在IACS后A1C升高幅度大于预期(实际A1C≥预测值的0.5%)。A1C高于预期的升高仅与基线A1C相关(基线A1C的比值比[OR]1.84(95%CI 1.08-1.13)为7.0-8.0%,而基线A1C为8.0%,而<7.0%为8.0%。尽管大多数患者在IACS后A1C没有增加,但临床医生应就IACS给药后糖尿病控制不佳的患者进一步高血糖的风险向其提供建议。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinical Diabetes
Clinical Diabetes Medicine-Internal Medicine
CiteScore
4.30
自引率
0.00%
发文量
93
期刊介绍: The mission of Clinical Diabetes is to provide primary care providers and all clinicians involved in the care of people with diabetes with information on advances and state-of-the-art care for people with diabetes. Clinical Diabetes is also a forum for discussing diabetes-related problems in practice, medical-legal issues, case studies, digests of recent research, and patient education materials.
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