A Randomized Two Stage Adaptively Censored Design With Application to Testing

Q3 Mathematics

Revista Colombiana De Estadistica Pub Date : 2019-07-01 DOI:10.15446/RCE.V42N2.65344

U. Bandyopadhyay, Rahul Bhattacharya

引用次数: 0

Abstract

A two stage randomized design is developed for two treatment clinical trials in which response variables are exponential and the observations are censored by using failure censoring and time censoring in the first and second stages respectively. The censoring time for the second stage is determined from the outcomes of the first stage. An application to testing for the equality of treatment effects is given along with a comparative study with relevant properties.

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随机两阶段自适应截尾设计及其在测试中的应用

为两个治疗临床试验开发了两阶段随机设计，其中反应变量为指数型，观察结果分别在第一阶段和第二阶段通过失败审查和时间审查进行审查。第二阶段的审查时间由第一阶段的审查结果确定。本文给出了一种检验治疗效果公平性的应用，并与相关性质进行了比较研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Colombiana De Estadistica STATISTICS & PROBABILITY-

CiteScore

1.20

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Colombian Journal of Statistics publishes original articles of theoretical, methodological and educational kind in any branch of Statistics. Purely theoretical papers should include illustration of the techniques presented with real data or at least simulation experiments in order to verify the usefulness of the contents presented. Informative articles of high quality methodologies or statistical techniques applied in different fields of knowledge are also considered. Only articles in English language are considered for publication. The Editorial Committee assumes that the works submitted for evaluation have not been previously published and are not being given simultaneously for publication elsewhere, and will not be without prior consent of the Committee, unless, as a result of the assessment, decides not publish in the journal. It is further assumed that when the authors deliver a document for publication in the Colombian Journal of Statistics, they know the above conditions and agree with them.