Relación entre los índices plaquetarios en colecistitis aguda: un estudio de casos y controles

IF 1.5 Q3 GASTROENTEROLOGY & HEPATOLOGY

Revista de Gastroenterologia de Mexico Pub Date : 2024-04-01 DOI:10.1016/j.rgmx.2023.04.004

S. Özdemir , İ. Altunok , A. Özkan , M.M. İslam , A. Algın , S.E. Eroğlu , G. Aksel

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引用次数: 0

Abstract

Introduction and aims

We aimed to investigate changes in initial platelet indices in patients arriving at the emergency department with acute cholecystitis.

Material and methods

A retrospective case-control study was conducted at a tertiary care teaching hospital. Demographics, comorbidities, laboratory data, length of hospital stay, and mortality data for the acute cholecystitis group were retrospectively obtained from the hospital digital database. Platelet count, mean platelet volume, plateletcrit, platelet distribution width, and platelet mass index were collected.

Results

A total of 553 patients with acute cholecystitis were the study cases, and 541 hospital employees were the study controls. According to the results of the multivariate analysis of the platelet indices studied, only mean platelet volume and platelet distribution width showed significant differences between the two groups (adjusted odds ratio: 2; 95% confidence interval: 1.4-2.7; P < .001 and adjusted odds ratio: 5.88; 95% confidence interval: 2.44-14.4; P < .001, respectively). The multivariate regression model created had an area under the curve of 0.969 in the prediction of acute cholecystitis (accuracy: 0.917; sensitivity: 89%; specificity: 94.5%).

Conclusion

The study results indicate that the initial mean platelet volume and platelet distribution width were independent predictors of acute cholecystitis.

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急性胆囊炎血小板指数的关系:病例与对照研究

材料与方法在一家三级甲等教学医院开展了一项回顾性病例对照研究。急性胆囊炎组的人口统计学、合并症、实验室数据、住院时间和死亡率数据均从医院数字数据库中回顾性获得。研究还收集了血小板计数、血小板平均体积、血小板crit、血小板分布宽度和血小板质量指数。根据所研究的血小板指数的多变量分析结果，只有平均血小板体积和血小板分布宽度在两组之间存在显著差异（调整后的几率比：2；95% 置信区间：1.4-2.7；P <.001；调整后的几率比：5.88；95% 置信区间：2.44-14.4；P <.001）。研究结果表明，初始平均血小板体积和血小板分布宽度是急性胆囊炎的独立预测指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista de Gastroenterologia de Mexico GASTROENTEROLOGY & HEPATOLOGY-

CiteScore

1.60

自引率

12.50%

发文量

102

审稿时长

12 weeks

期刊介绍： La Revista de Gastroenterología de México es el órgano oficial de la Asociación Mexicana de Gastroenterología. Sus espacios están abiertos a los miembros de la Asociación como a todo miembro de la comunidad médica que manifieste interés por utilizar este foro para publicar sus trabajos, cumpliendo con las políticas editoriales que a continuación se mencionan. El objetivo principal de la Revista de Gastroenterología de México, es publicar trabajos originales del amplio campo de la gastroenterología, así como proporcionar información actualizada y relevante para el área de la especialidad y áreas afines. Los trabajos científicos incluyen las áreas de Gastroenterología clínica, endoscópica, quirúrgica y pediátrica.