Design and fabrication of 125I seeds for brachytherapy using capillary-based microfluidic technique

IF 0.7 4区物理与天体物理 Q4 CHEMISTRY, INORGANIC & NUCLEAR

Nukleonika Pub Date : 2021-06-01 DOI:10.2478/nuka-2021-0007

Yuan-Yuan Wang, Miao Zhang, Tong Song, Zhenqi Chang

引用次数: 0

Abstract

Abstract A new kind of 125I seeds with a core-shell structure were synthesized by an easy assembling–disassembling coaxial capillaries microfluidic device. The dose distribution of a 125I brachytherapy source fabricated by arranging six 125I seeds collinearly within a cylindrical titanium capsule was simulated by modelling the source in a water phantom using Monte Carlo N-Particle Transport code. The influence of the motion and the core size of the 125I seeds on the dose distribution was also studied in this work.

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基于毛细管微流控技术的近距离治疗用125I粒子的设计与制备

摘要采用易于拆装的同轴毛细管微流体装置，合成了一种具有核壳结构的新型125I晶种。通过使用蒙特卡罗N粒子传输代码在水模型中模拟125I近距离放射源，模拟了通过在圆柱形钛胶囊内共线布置六个125I种子而制造的125I近近距离放射治疗源的剂量分布。本工作还研究了125I种子的运动和核大小对剂量分布的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nukleonika 物理-无机化学与核化学

CiteScore

2.00

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： "Nukleonika" is an international peer-reviewed, scientific journal publishing original top quality papers on fundamental, experimental, applied and theoretical aspects of nuclear sciences. The fields of research include: radiochemistry, radiation measurements, application of radionuclides in various branches of science and technology, chemistry of f-block elements, radiation chemistry, radiation physics, activation analysis, nuclear medicine, radiobiology, radiation safety, nuclear industrial electronics, environmental protection, radioactive wastes, nuclear technologies in material and process engineering, radioisotope diagnostic methods of engineering objects, nuclear physics, nuclear reactors and nuclear power, reactor physics, nuclear safety, fuel cycle, reactor calculations, nuclear chemical engineering, nuclear fusion, plasma physics etc.