Prevalence of chronic kidney disease and associated factors among patients with underlying chronic disease at Dessie Referral Hospital, East Amhara Region, Ethiopia.

Frontiers in epidemiology Pub Date : 2023-07-18 eCollection Date: 2023-01-01 DOI:10.3389/fepid.2023.1154522
Ahmed Ali, Kebadnew Mulatu, Sefineh Fenta Feleke, Gizachew Tadesse Wassie
{"title":"Prevalence of chronic kidney disease and associated factors among patients with underlying chronic disease at Dessie Referral Hospital, East Amhara Region, Ethiopia.","authors":"Ahmed Ali, Kebadnew Mulatu, Sefineh Fenta Feleke, Gizachew Tadesse Wassie","doi":"10.3389/fepid.2023.1154522","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease is defined as a reduction in glomerular filtration rate below 60 ml/min per 1.73 m<sup>2</sup> and presence of albuminuria over a period of time. Globally, 10%-15% of populations are affected by chronic kidney disease. Studies conducted in Jimma, Addis Ababa, and the Tigray region were conducted on a single chronic disease and did not include human immune viruses. In addition, there has been no such study conducted in the Amhara region. Therefore, the aim of this study was to determine the magnitude and associated factors of chronic kidney disease among chronic patients who are followed up at an outpatient department.</p><p><strong>Methods: </strong>An institutional-based cross-sectional study of 480 chronic patients was conducted at Dessie Referral Hospital, Dessie, Ethiopia between 15 March and 16 April 2020. Data were entered into Epidata and exported to SPSS version 25 for analysis. Binary logistic regression models were performed to identify factors associated with chronic kidney disease. The variables with a <i>p</i>-value ≤0.25 were considered to be a candidate for multivariable logistic regression. A <i>p</i>-value ≤0.05 was considered a statistically significant association.</p><p><strong>Results: </strong>The magnitude of chronic kidney disease among the study participants was 21.3%. Variables such as hypertension [adjusted odds ratio (AOR): 2.6, 95% CI: 1.58-4.27], use of non-steroidal anti-inflammatory drugs (AOR: 2.4, 95% CI: 1.41-3.97), smoking (AOR: 4.4, 95% CI: 2.65-7.34), routine physical activity (AOR: 0.6, 95% CI: 0.35-0.94), and obesity (AOR: 3.0, 95% CI: 1.76-5.05) were significantly associated with the chronic kidney disease.</p><p><strong>Conclusion: </strong>This study found that the magnitude of chronic kidney disease in the study area was high. Hypertension, use of non-steroidal anti-inflammatory drugs, smoking, routine physical activity, and obesity were found to be significant factors for chronic kidney disease.</p>","PeriodicalId":73083,"journal":{"name":"Frontiers in epidemiology","volume":" ","pages":"1154522"},"PeriodicalIF":0.0000,"publicationDate":"2023-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10910998/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Frontiers in epidemiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/fepid.2023.1154522","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Chronic kidney disease is defined as a reduction in glomerular filtration rate below 60 ml/min per 1.73 m2 and presence of albuminuria over a period of time. Globally, 10%-15% of populations are affected by chronic kidney disease. Studies conducted in Jimma, Addis Ababa, and the Tigray region were conducted on a single chronic disease and did not include human immune viruses. In addition, there has been no such study conducted in the Amhara region. Therefore, the aim of this study was to determine the magnitude and associated factors of chronic kidney disease among chronic patients who are followed up at an outpatient department.

Methods: An institutional-based cross-sectional study of 480 chronic patients was conducted at Dessie Referral Hospital, Dessie, Ethiopia between 15 March and 16 April 2020. Data were entered into Epidata and exported to SPSS version 25 for analysis. Binary logistic regression models were performed to identify factors associated with chronic kidney disease. The variables with a p-value ≤0.25 were considered to be a candidate for multivariable logistic regression. A p-value ≤0.05 was considered a statistically significant association.

Results: The magnitude of chronic kidney disease among the study participants was 21.3%. Variables such as hypertension [adjusted odds ratio (AOR): 2.6, 95% CI: 1.58-4.27], use of non-steroidal anti-inflammatory drugs (AOR: 2.4, 95% CI: 1.41-3.97), smoking (AOR: 4.4, 95% CI: 2.65-7.34), routine physical activity (AOR: 0.6, 95% CI: 0.35-0.94), and obesity (AOR: 3.0, 95% CI: 1.76-5.05) were significantly associated with the chronic kidney disease.

Conclusion: This study found that the magnitude of chronic kidney disease in the study area was high. Hypertension, use of non-steroidal anti-inflammatory drugs, smoking, routine physical activity, and obesity were found to be significant factors for chronic kidney disease.

埃塞俄比亚东阿姆哈拉地区Dessie转诊医院慢性肾病患者的患病率及相关因素
慢性肾脏疾病的定义是肾小球滤过率在一段时间内低于60ml /min / 1.73 m2,并且存在蛋白尿。在全球范围内,10%-15%的人口受到慢性肾脏疾病的影响。在吉马、亚的斯亚贝巴和提格雷地区进行的研究是针对一种慢性病进行的,不包括人类免疫病毒。此外,在阿姆哈拉地区也没有进行这种研究。因此,本研究的目的是确定在门诊随访的慢性患者中慢性肾脏疾病的程度和相关因素。2020年3月15日至4月16日,在埃塞俄比亚德西转诊医院对480名慢性患者进行了一项基于机构的横断面研究。数据输入Epidata,导出到SPSS 25进行分析。采用二元logistic回归模型来确定与慢性肾脏疾病相关的因素。p值≤0.25的变量被认为是多变量逻辑回归的候选变量。p值≤0.05被认为具有统计学意义。研究参与者中慢性肾脏疾病的发生率为21.3%。高血压[调整优势比(AOR): 2.6, 95% CI: 1.58-4.27]、使用非甾体抗炎药(AOR: 2.4, 95% CI: 1.41-3.97)、吸烟(AOR: 4.4, 95% CI: 2.65-7.34)、常规体育活动(AOR: 0.6, 95% CI: 0.35-0.94)和肥胖(AOR: 3.0, 95% CI: 1.76-5.05)等变量与慢性肾脏疾病显著相关。本研究发现,研究地区慢性肾脏疾病的严重程度较高。高血压、使用非甾体抗炎药、吸烟、常规体育活动和肥胖被发现是慢性肾脏疾病的重要因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信