Frequency of dyslipidemia and other cardiovascular risk factors in patients with rheumatoid arthritis

Dora Elizabeth Montiel de Jarolín, Sandra Holtzberger, C. Gill
{"title":"Frequency of dyslipidemia and other cardiovascular risk factors in patients with rheumatoid arthritis","authors":"Dora Elizabeth Montiel de Jarolín, Sandra Holtzberger, C. Gill","doi":"10.18004/RDN2018.010.02.093-104","DOIUrl":null,"url":null,"abstract":"Introduction: rheumatoid arthritis (RA) is an autoimmune, inflammatory, chronic and systemic disease characterized by a progressive functional deterioration. Cardiovascular disease associated with atherosclerotic events is one of the causes of morbidity and mortality in patients with RA. Objective: to determine the frequency of dyslipidemia and other cardiovascular risk factors in patients with RA who consult the Day Hospital of the National Hospital of Itauguá in the period January 2018-March 2018. Material and Method: descriptive observational study of transverse section. We included 45 patients with RA who were determined serum lipid profile. The results were classified according to the modified report in 2004 of the Third Adult Treatment Panel (ATP III). In addition, the activity of the disease, the body mass index, the associated cardiovascular risk factors (hypertension, diabetes mellitus, sedentary lifestyle, use of corticosteroids) were determined. DEL NACIONAL Rev. Nac. (Itauguá) 2018;10(2):093-104 doi: 10.18004/rdn2018.010.02.093-104 Results: 45 patients were included, 36 women (80%), 9 males (20%), 48 ± 14 mean age, 54.8 ± 64 months mean disease time, 27 (60%) inactive arthritis, 18 active arthritis (60%). 40%). CRP presented mean 1.6 ± 2.7 mg / dL, mean erythrocytes 28.5 ± 18.7 mm / 1 ° h, dyslipidemia 17 (38%), mean total cholesterol 189 ± 42.3 mg / dL, hypercholesterolemia 16 (36%), average LDL-C of 97 mg / dL, HDL-C mean 44.5 mg / dL, HDL-c low 18 (40%), mean triglycerides 140 mg / dL, hypertriglyceridemia 11 (25%), mean glycemia 95 mg / dL. They had high blood pressure 11 (24.4%), diabetes mellitus 2 (4.4%), use of corticosteroids 24 (55%), average daily dose of prednisone 10 mg, sedentary lifestyle 28 (65%), mean BMI 27 ± 6 , 2 k / m2, overweight 13 (29%), obesity 10 (22%). The activity of the disease was not statistically significant with dyslipidemia (p 0.6) but the use of prednisone was statistically significant in relation to the presence of low HDL-c. Conclusion: the frequency of dyslipidemia was 38%, the main associated risk factors were sedentary lifestyle and overweight / obesity.","PeriodicalId":52884,"journal":{"name":"Revista del Nacional Itaugua","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista del Nacional Itaugua","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18004/RDN2018.010.02.093-104","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: rheumatoid arthritis (RA) is an autoimmune, inflammatory, chronic and systemic disease characterized by a progressive functional deterioration. Cardiovascular disease associated with atherosclerotic events is one of the causes of morbidity and mortality in patients with RA. Objective: to determine the frequency of dyslipidemia and other cardiovascular risk factors in patients with RA who consult the Day Hospital of the National Hospital of Itauguá in the period January 2018-March 2018. Material and Method: descriptive observational study of transverse section. We included 45 patients with RA who were determined serum lipid profile. The results were classified according to the modified report in 2004 of the Third Adult Treatment Panel (ATP III). In addition, the activity of the disease, the body mass index, the associated cardiovascular risk factors (hypertension, diabetes mellitus, sedentary lifestyle, use of corticosteroids) were determined. DEL NACIONAL Rev. Nac. (Itauguá) 2018;10(2):093-104 doi: 10.18004/rdn2018.010.02.093-104 Results: 45 patients were included, 36 women (80%), 9 males (20%), 48 ± 14 mean age, 54.8 ± 64 months mean disease time, 27 (60%) inactive arthritis, 18 active arthritis (60%). 40%). CRP presented mean 1.6 ± 2.7 mg / dL, mean erythrocytes 28.5 ± 18.7 mm / 1 ° h, dyslipidemia 17 (38%), mean total cholesterol 189 ± 42.3 mg / dL, hypercholesterolemia 16 (36%), average LDL-C of 97 mg / dL, HDL-C mean 44.5 mg / dL, HDL-c low 18 (40%), mean triglycerides 140 mg / dL, hypertriglyceridemia 11 (25%), mean glycemia 95 mg / dL. They had high blood pressure 11 (24.4%), diabetes mellitus 2 (4.4%), use of corticosteroids 24 (55%), average daily dose of prednisone 10 mg, sedentary lifestyle 28 (65%), mean BMI 27 ± 6 , 2 k / m2, overweight 13 (29%), obesity 10 (22%). The activity of the disease was not statistically significant with dyslipidemia (p 0.6) but the use of prednisone was statistically significant in relation to the presence of low HDL-c. Conclusion: the frequency of dyslipidemia was 38%, the main associated risk factors were sedentary lifestyle and overweight / obesity.
类风湿性关节炎患者血脂异常及其他心血管危险因素的发生频率
类风湿关节炎(RA)是一种自身免疫、炎症、慢性和全身性疾病,以进行性功能恶化为特征。与动脉粥样硬化事件相关的心血管疾病是RA患者发病和死亡的原因之一。目的:了解2018年1月- 2018年3月在伊塔奥古国立医院日间医院就诊的RA患者血脂异常及其他心血管危险因素的发生频率。材料和方法:横切面描述性观察研究。我们纳入了45例RA患者,测定了他们的血脂水平。结果根据2004年第三次成人治疗小组(ATP III)的修订报告进行分类。此外,还确定了疾病的活动性、体重指数、相关心血管危险因素(高血压、糖尿病、久坐不动的生活方式、皮质类固醇的使用)。国家牧师:[itaugu] 2018;10(2):093-104 doi: 10.18004/rdn2018.010.02.093-104结果:纳入45例患者,女性36例(80%),男性9例(20%),平均年龄48±14岁,平均发病时间54.8±64个月,非活动性关节炎27例(60%),活动性关节炎18例(60%)。40%)。CRP平均为1.6±2.7 mg / dL,平均红细胞28.5±18.7 mm / 1°h,血脂异常17(38%),平均总胆固醇189±42.3 mg / dL,高胆固醇血症16(36%),平均LDL-C为97 mg / dL,平均HDL-C为44.5 mg / dL, HDL-C低18(40%),平均甘油三酯为140 mg / dL,高甘油三酯为11(25%),平均血糖为95 mg / dL。他们有高血压11例(24.4%),糖尿病2例(4.4%),使用皮质类固醇24例(55%),强的松平均日剂量10 mg,久坐生活方式28例(65%),平均BMI为27±6,2 k / m2,超重13例(29%),肥胖10例(22%)。疾病的活动性与血脂异常无统计学意义(p0.6),但泼尼松的使用与低HDL-c的存在有统计学意义。结论:血脂异常发生率为38%,主要危险因素为久坐生活方式和超重/肥胖。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
0.40
自引率
0.00%
发文量
11
审稿时长
4 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信