The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent

IF 1.2 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Comptes Rendus. Chimie Pub Date : 2022-10-12 DOI:10.5802/crchim.206

Khee Chung Hui, Nagaammai Dhanapalan, A. C. Khayrani, Teguh Imanto, N. S. Sambudi

引用次数: 1

Abstract

The synthesis of amino-functionalized carbon quantum dots-decorated hydroxyapatite as drug delivery agent Abstract. Hydroxyapatite (HAp) was combined with amino-functionalized carbon quantum dots (CQDs) to enhance the optical and surface area properties of HAp. The loading of amino-functionalized CQDs could enhance the luminescence of HAp and its UV–Vis absorbance. Ad-ditionally, surface area of HAp could be increased from 84.16 to 129.94 m 2 /g by loading amino-functionalized CQDs. The drug release experiment was conducted using acetaminophen. The release happened slowly for amino-functionalized CQDs/HAp, with full release of acetaminophen being observed after 24 h. The enhanced luminescence composite shows high potential for the composite to be used for the controlled release of drugs.

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氨基功能化碳量子点修饰羟基磷灰石的合成

氨基功能化碳量子点修饰羟基磷灰石作为药物递送剂的合成摘要。将羟基磷灰石（HAp）与氨基官能化碳量子点（CQDs）相结合，以增强HAp的光学和表面积性能。氨基官能化CQDs的负载可以增强HAp的发光及其紫外-可见吸收。有条件地，通过负载氨基官能化的CQD，HAp的表面积可以从84.16增加到129.94m2/g。使用对乙酰氨基酚进行药物释放实验。氨基官能化CQDs/HAp的释放缓慢，24小时后观察到对乙酰氨基酚的完全释放。增强发光复合物显示出该复合物用于药物控释的高潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Comptes Rendus. Chimie 化学-化学综合

CiteScore

2.10

自引率

25.00%

发文量

审稿时长

3 months

期刊介绍： The Comptes Rendus - Chimie are a free-of-charge, open access and peer-reviewed electronic scientific journal publishing original research articles. It is one of seven journals published by the Académie des sciences. Its objective is to enable researchers to quickly share their work with the international scientific community. The Comptes Rendus - Chimie also publish journal articles, thematic issues and articles reflecting the history of the Académie des sciences and its current scientific activity.