Therapeutic effect of acitretin combined with traditional Chinese Medicine on pustular psoriasis

中国基层医药 Pub Date : 2020-03-01 DOI:10.3760/CMA.J.ISSN.1008-6706.2020.05.013

L. Qin

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引用次数: 0

Abstract

Objective To observe the efficacy of acitretin combined with traditional Chinese medicine in the treatment of pustular psoriasis. Methods From July 2011 to October 2017, 91 patients with pustular psoriasis admitted to the Second People's Hospital of Changzhi were randomly divided into treatment group(n=31), control group Ⅰ (n=30) and control group Ⅱ(n=30) according to the digital table.The patients in the three groups were treated with acitretin combined with traditional Chinese medicine, oral acitretin and traditional Chinese medicine, respectively.The therapeutic effects, the time required for hypothermia, the time required for the complete disappearance of pustules and the average length of hospitalization were compared among the three groups. Results The total effective rate was 93.55%(29/31) in the treatment group, 70.00%(21/30) in the control group Ⅰ and 73.33%(22/30) in the control group Ⅱ.The total effective rate in the treatment group was significantly higher than that in the two control groups(χ2=5.720, 4.546, all P 0.05). The fever allaying time, completely disappearance time of pustules, average hospital stay in the treatment group were (4.24±0.86)d, (7.38±0.72)d, (23.46±0.61)d, respectively, which in the control group Ⅰ were (7.45±0.92)d, (10.45±0.52)d, (30.01±0.82)d, respectively, which in the control group Ⅱ were (8.56±0.78)d, (11.56±0.35)d, (31.53±0.68)d, respectively, which in the control group Ⅰ were significantly shorter than those in the control group Ⅱ(t=14.083, 19.037, 35.476, all P<0.05), which in the treatment group were significantly lower than those in the control group Ⅰ and the control group Ⅱ(t=20.529, 28.682, 48.826, 5.041, 9.699, 7.816, all P<0.05). Conclusion Acitretin capsule combined with traditional Chinese medicine is effective in the treatment of pustular psoriasis, which can control body temperature in a short time, shorten the time of disappearance of pustule, relieve the pain of patients, and shorten the time of hospitalization at the same time. Key words: Psoriasis; Skin diseases; Avera; Drugs, chinese herbal; Drug therapy, combination; Treatment outcome; Comparative study

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阿曲汀联合中药治疗脓疱性银屑病疗效观察

目的观察阿曲汀联合中药治疗脓疱性银屑病的疗效。方法将长治市第二人民医院2011年7月至2017年10月收治的91例脓疱型银屑病患者，按数字表随机分为治疗组（n=31）、对照组Ⅰ（n=30）和对照组Ⅱ（n=30。三组患者分别采用阿曲汀联合中药、口服阿曲汀和中药治疗。比较三组患者的治疗效果、体温过低所需时间、脓疱完全消失所需时间和平均住院时间。结果治疗组总有效率为93.55%（29/31），对照组Ⅰ为70.00%（21/30），对照对照组Ⅱ为73.33%（22/30），治疗组的平均住院时间分别为（4.24±0.86）d、（7.38±0.72）d和（23.46±0.61）d，对照组Ⅰ分别为（7.45±0.92）d、，对照组Ⅰ明显短于对照组Ⅱ（t=14.083、19.037、35.476，均P<0.05），治疗组明显低于对照组Ⅰ和对照组Ⅱ（t=20.529，28.682，48.826，5.041，9.699，7.816，均P<0.05），缩短脓疱消失的时间，减轻患者的痛苦，同时缩短住院时间。关键词：银屑病；皮肤病；Avera；药物、中草药；药物治疗，联合用药；治疗结果；比较研究

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来源期刊

中国基层医药

CiteScore

0.10

自引率

0.00%

发文量

32251

期刊介绍： Since its inception, the journal "Chinese Primary Medicine" has adhered to the development strategy of "based in China, serving the grassroots, and facing the world" as its publishing concept, reporting a large amount of the latest medical information at home and abroad, prospering the academic field of primary medicine, and is praised by readers as a medical encyclopedia that updates knowledge. It is a core journal in China's medical and health field, and its influence index (CI) ranks Q2 in China's academic journals in 2022. It was included in the American Chemical Abstracts in 2008, the World Health Organization Western Pacific Regional Medical Index (WPRIM) in 2009, and the Japan Science and Technology Agency Database (JST) and Scopus Database in 2018, and was included in the Wanfang Data-China Digital Journal Group and the China Academic Journal Comprehensive Evaluation Database.