Microwave-Assisted, [Bmim]PF6-Catalyzed Synthesis of Benzoxazoles under Solvent-free Conditions

IF 0.9 Q4 CHEMISTRY, PHYSICAL

Current Organocatalysis Pub Date : 2022-12-14 DOI:10.2174/2213337210666221214121957

D. Duc

引用次数: 0

Abstract

An efficient and green strategy for the synthesis of 2-arylbenzoxazoles catalyzed by [Bmim]PF6 ionic liquid has been investigated via the condensation of o-aminophenol with aldehydes. The microwave-assisted synthesis features some advantages such as good yield of products, broad substrate scope, simple product purification, and absence of metal catalyst and solvent. Furthermore, the synthesis could be conveniently expanded to a gram scale.

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微波辅助[Bmim] pf6无溶剂催化合成苯并恶唑

研究了邻氨基酚与醛的缩合反应在[Bmim]PF6离子液体催化下合成2-芳基苯并恶唑的高效、绿色策略。微波辅助合成具有产物收率高、底物范围广、产物纯化简单、不需要金属催化剂和溶剂等优点。此外，该合成可以方便地扩展到克尺度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Organocatalysis CHEMISTRY, PHYSICAL-

CiteScore

2.00

自引率

0.00%

发文量

期刊介绍： Current Organocatalysis is an international peer-reviewed journal that publishes significant research in all areas of organocatalysis. The journal covers organo homogeneous/heterogeneous catalysis, innovative mechanistic studies and kinetics of organocatalytic processes focusing on practical, theoretical and computational aspects. It also includes potential applications of organocatalysts in the fields of drug discovery, synthesis of novel molecules, synthetic method development, green chemistry and chemoenzymatic reactions. This journal also accepts papers on methods, reagents, and mechanism of a synthetic process and technology pertaining to chemistry. Moreover, this journal features full-length/mini review articles within organocatalysis and synthetic chemistry. It is the premier source of organocatalysis and synthetic methods related information for chemists, biologists and engineers pursuing research in industry and academia.