Evaluation of the Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio in Patients With Ectopic Pregnancies

S. Gencdal, H. Aydoğmuş, N. Gencdal, Emre Destegul, E. Ekmekci
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引用次数: 1

Abstract

Background: The aim of this study was to evaluate hematologic parameters in ectopic pregnancy. Methods: This retrospective study was conducted at Izmir Katip Celebi University Ataturk Education and Research Hospital between January 2016 and June 2017. The medical records of 97 patients hospitalised for ectopic pregnancy (EP) were summarised. The control group consisted of 112 women at 6 - 8 weeks, healthy, intrauterine gestations as confirmed by ultrasound (positive fetal heart rates). Hematologic parameters including white blood cells, hemoglobin and platelet counts, neutrophil-lymphocyte ratio (NLR), platelet-lymphocyte ratio (PLR), and mean platelet volume (MPV) were compared. Results: In total, 209 patients were included in the study: 112 with healthy pregnancies and 97 with EPs. There was no statistically significant difference between the groups regarding mean age, gravidity, parity, number of abortions, body mass index, history for previous cesarean deliveries, and previous EPs. The MPV level was lower in the EP group than in the control group. In addition, the mean NLR was higher in the EP group than in the controls. Conclusions: Considering the sensitivity and specificity, overall, the NLR and MPV has moderate diagnostic potential in patients with ectopic pregnancies. J Clin Gynecol Obstet. 2019;8(3):81-84 doi: https://doi.org/10.14740/jcgo559
异位妊娠患者中性粒细胞-淋巴细胞比率和血小板-淋巴细胞比率的评价
背景:本研究的目的是评估异位妊娠的血液学参数。方法:本回顾性研究于2016年1月至2017年6月在伊兹密尔卡蒂普·塞莱比大学阿塔图尔克教育研究医院进行。总结了97例因异位妊娠住院的患者的医疗记录。对照组包括112名6-8周的健康宫内妊娠妇女(胎儿心率阳性)。比较血液学参数,包括白细胞、血红蛋白和血小板计数、中性粒细胞淋巴细胞比率(NLR)、血小板淋巴细胞比率(PLR)和平均血小板体积(MPV)。结果:总共有209名患者被纳入研究:112名健康妊娠,97名EPs。两组在平均年龄、妊娠率、产次、流产次数、体重指数、既往剖宫产史和既往EPs方面没有统计学上的显著差异。EP组的MPV水平低于对照组。此外,EP组的平均NLR高于对照组。结论:考虑到敏感性和特异性,总体而言,NLR和MPV对异位妊娠患者具有中等的诊断潜力。《临床妇科产科杂志》。2019年;8(3):81-84 doi:https://doi.org/10.14740/jcgo559
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