The impact of young adult colorectal cancer: incidence and trends in Colorado

IF 2.7 Q3 ONCOLOGY

Colorectal Cancer Pub Date : 2017-11-08 DOI:10.2217/CRC-2017-0008

D. W. Sheneman, Jack L Finch, W. Messersmith, S. Leong, K. Goodman, S. Davis, W. Thomas Purcell, M. McCarter, C. Gajdos, J. Vogel, S. Eckhardt, Christopher H Lieu

引用次数: 10

Abstract

Aim: Far less is known about colorectal cancer (CRC) incidence in individuals under the age of 50. This study examined CRC incidence in order to better understand the changing CRC population. Methods: This study analyzed 39,525 CRC cases from the Colorado Central Cancer Registry from 1992 through 2013. Age-adjusted incidence, observed and relative 5-year survival, and estimated annual percentage change was analyzed. Results: Age-adjusted rates averaging 1.7% per year were observed in the under-50 population, while falling on average 4.3% per year (p < 0.05) in the over-50 population. Average-adjusted incidence rose in males under 50 by 2.7% per year (p < 0.05). Conclusion: The absolute incidence of CRC continues to fall in Colorado, however incidence is rising in individuals under 50, particularly males.

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年轻人癌症的影响：科罗拉多州的发病率和趋势

目的：人们对50岁以下人群结直肠癌（CRC）的发病率知之甚少。本研究检查了CRC的发病率，以便更好地了解不断变化的CRC人群。方法：本研究分析了1992年至2013年科罗拉多州癌症中心登记的39525例CRC病例。分析年龄调整后的发病率、观察到的和相对的5年生存率以及估计的年百分比变化。结果：50岁以下人群的年龄调整率平均每年1.7%，而50岁以上人群的年龄校正率平均每年下降4.3%（p<0.05）。50岁以下男性的平均调整后发病率每年上升2.7%（p<0.05）。结论：科罗拉多州CRC的绝对发病率继续下降，但50岁以下人群的发病率正在上升，尤其是男性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Colorectal Cancer ONCOLOGY-

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期刊介绍： Colorectal cancer is a major cause of morbidity and mortality, particularly in the developed world. Risk factors for colorectal cancer are on the rise in many countries; populations are aging, and obesity and diabetes are increasing. National screening programs are helping to detect cancer while it is still curable; however, colorectal cancer remains the third leading cause of cancer deaths in the USA and options are still limited for those with more advanced disease. Consequently, colorectal cancer is a major research priority for government, pharmaceutical companies and non-profit organizations. Research into diagnosis and optimum treatment of the disease is progressing rapidly, with new advances reported every day. Colorectal Cancer presents reviews, analysis and commentary. on all aspects of colorectal cancer.