Injeção intra‐articular de hexacetonido de triancinolona em pacientes com artrite reumatoide: avaliação prospectiva da goniometria e parâmetros de inflamação articular

Q Medicine

Revista Brasileira De Reumatologia Pub Date : 2017-03-01 DOI:10.1016/j.rbr.2016.06.006

Rita Nely Vilar Furtado, Flávia Soares Machado, Karine Rodrigues da Luz, Marla Francisca dos Santos, Monique Sayuri Konai, Roberta Vilela Lopes, Jamil Natour

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引用次数: 3

Abstract

Objectives

To evaluate local joint variables after intra‐articular injection (IAI) with triamcinolone hexacetonide (HT) in rheumatoid arthritis (RA) patients.

Methods

We blindly and prospectively (baseline, 1, 4, 12 and 24 weeks) evaluated metacarpophalangeal (MCP), wrist, elbow, shoulder, knee and ankle joints after HT IAI by the following outcome measures: Visual analogue scale 0‐10 cm (VAS) for rest pain (VASR); VAS for movement pain (VASM); VAS for joint swelling (VASSw); flexion (FlexG) and extension (ExtG).

Results

289 patients (635 joints) were studied. VASSw (p < 0,001) and VASR (0,001< p < 0.016) improved from T0 to T4, T12 and T24 for all joints. VASM improved from T0‐T4 (p < 0.021) for all joints; T0‐T12 (p < 0.023) for MCF and knee; T0‐T24 (p < 0.019) only for MCF and knee. FlexG improved from T0‐T4 (p < 0.001) for all joints; T0‐T12 (p < 0.001) and T0‐T24 (p < 0.02) only for MCF and knee. ExtG improved from T0‐T4 (p < 0.001) for all joints except for elbow; T0‐T12 (p = 0.003) for wrist, MCP and knee; and T0‐T24 (p = 0.014) for MCF and knee.

Conclusion

VASSw responded better at short and medium term after IAI with HT in our sample of RA patients.

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类风湿性关节炎关节内注射曲安奈德六酮:角度测量和关节炎症参数的前瞻性评价

目的评价类风湿性关节炎(RA)患者关节内注射曲安奈德(HT)后的局部关节变量。方法采用盲法和前瞻性(基线、1、4、12和24周)评估HT IAI后掌指关节(MCP)、腕、肘、肩、膝和踝关节的预后指标:静止疼痛(VASR)的视觉模拟评分0 ~ 10 cm;VAS治疗运动痛(VASM);关节肿胀VAS (vasw);屈(FlexG)和伸(ExtG)。结果289例患者共635个关节。w & p;0,001)和VASR (0,001<p & lt;0.016)，各关节从T0到T4、T12和T24均有改善。VASM从T0‐T4改善(p <所有接头0.021);T0‐T12 (p <MCF和膝关节0.023);T0‐T24 (p <0.019)仅适用于MCF和膝关节。从T0‐T4改进的FlexG (p <0.001);T0‐T12 (p <0.001)和T0‐T24 (p <0.02)，仅适用于MCF和膝关节。从T0‐T4改进的ExtG (p <0.001)，除肘关节外的所有关节;手腕、MCP和膝关节的T0‐T12 (p = 0.003);MCF和膝关节的T0 - T24 (p = 0.014)。结论在我们的RA患者样本中，在IAI联合HT后，vassw在中短期疗效更好。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Revista Brasileira De Reumatologia RHEUMATOLOGY-

CiteScore

0.82

自引率

0.00%

发文量

审稿时长

6-12 weeks

期刊介绍： RBR nasceu da necessidade de se criar um órgão oficial da SBR que pudesse divulgar a produção científica dos reumatologistas brasileiros. O primeiro número foi publicado em setembro de 1957. A partir do volume 18 (1978), passou a seis números, com periodicidade atual. A RBR, em sua trajetória, tem sido objeto de constantes mudanças, sempre visando ao seu aprimoramento e revitalização, tanto em sua apresentação como em seu conteúdo.