Factors associated with falls in frail older persons—a case control study in Brazil

IF 1 Q4 GERONTOLOGY
Thais Bueno Enes, Cristina Sanches, Lorena Rocha Ayres, Gustavo Machado Rocha, Laila Nathieline Gonçalves Rodrigues Madureira, Daniele Aparecida de Souza, Carl Schneider, Jéssica Azevedo Aquino, André Oliveira Baldoni
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Abstract

Method

This is a case-control study paired by sex and age, with the cases defined as frail older persons with self-reported falls in the last year and controls as frail older persons with no fall report. Odds ratio (OR) was analyzed by means of conditional logistic regression, with a 95% confidence interval. Main outcome measure: The occurrence of falls in frail older persons is associated with the following clinical and pharmacoepidemiological factors: urinary incontinence and polypharmacy.

Results

The sample consisted of 1028 older persons, 514 in the case group and 514 in the control group. The prevalence of falls was 26.5%. The frequency of polypharmacy, use of drugs inappropriate according to Beers’ criteria and drugs that increase the risk of falls were 58%, 85% and 87%. The frequency of drugs with anticholinergic properties ranged from 12 to 65% according to the type of scale used. It was observed that the fall is associated with urinary incontinence (OR 1.73, 95% CI 1.28–2.34) and use of five or more medications (OR 1.68, 95% CI, 1.30–2.17).

Conclusions

With this research, is possible to conclude that falling in the frail older persons is associated with the use of five or more drugs and the presence of urinary incontinence.

与体弱多病的老年人跌倒有关的因素——巴西的一项病例对照研究
方法这是一项按性别和年龄配对的病例对照研究,病例被定义为去年自我报告跌倒的体弱老年人,对照组被定义为没有跌倒报告的体弱老年。采用条件logistic回归分析比值比(OR),置信区间为95%。主要结果指标:体弱老年人跌倒的发生与以下临床和药物流行病学因素有关:尿失禁和多药治疗。结果本组老年人1028名,病例组514名,对照组514人。跌倒的患病率为26.5%。多药治疗、使用不符合Beers标准的药物以及增加跌倒风险的药物的频率分别为58%、85%和87%。根据使用的量表类型,具有抗胆碱能特性的药物的使用频率在12%至65%之间。据观察,跌倒与尿失禁(OR 1.73,95%CI 1.28-2.34)和使用五种或五种以上药物(OR 1.68,95%CI 1.30-2.17)有关。
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来源期刊
Ageing International
Ageing International GERONTOLOGY-
CiteScore
2.70
自引率
6.70%
发文量
39
期刊介绍: As a quarterly peer-reviewed journal that has existed for over three decades, Ageing International serves all professionals who deal with complex ageing issues. The journal is dedicated to improving the life of ageing populations worldwide through providing an intellectual forum for communicating common concerns, exchanging analyses and discoveries in scientific research, crystallizing significant issues, and offering recommendations in ageing-related service delivery and policy making. Besides encouraging the submission of high-quality research and review papers, Ageing International seeks to bring together researchers, policy analysts, and service program administrators who are committed to reducing the ''implementation gap'' between good science and effective service, between evidence-based protocol and culturally suitable programs, and between unique innovative solutions and generalizable policies. For significant issues that are common across countries, Ageing International will organize special forums for scholars and investigators from different disciplines to present their regional perspectives as well as to provide more comprehensive analysis. The editors strongly believe that such discourse has the potential to foster a wide range of coordinated efforts that will lead to improvements in the quality of life of older persons worldwide. Abstracted and Indexed in: ABI/INFORM, Academic OneFile, Academic Search, CSA/Proquest, Current Abstracts, EBSCO, Ergonomics Abstracts, Expanded Academic, Gale, Google Scholar, Health Reference Center Academic, OCLC, PsychINFO, PsyARTICLES, SCOPUS, Social Science Abstracts, and Summon by Serial Solutions.
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