Editorial - Do odontogenic tumors occur even in the dental clinic?

N. A. Nunes
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Abstract

Among the intra-osseous lesions, we find the root cysts very frequently. Due to the inflammatory process and involvement of the pulp, it is known to dentists. However, when think about odontogenic tumors, the frequent, painless odontoma often discovered on routine radiographs may come to mind. Easy to diagnose when compound.1 But what about other tumors derived from dental tissues? Ameloblastoma is a benign and relatively common neoplasm (10 to 49% of odontogenic tumors)1,2,3, originated of odontogenic epithelium, it may involve soft tissues (peripheral ameloblastoma) 4 or bone tissue of the maxilla and mandible, with a higher incidence in the mandible , with variable forms and histopathological classification, observed in young in the second and third decades of life or later.1,2,3 The radiographic and imaging aspects they may be unilocular or multilocular, resembling cystic lesion5,6 or multiple radiolucent areas2. Ameloblastomas present several histopathological types and the diagnosis allows more or less invasive treatments, since they tend to recur frequently7. From the damage produced to extensive surgeries and the need for reconstruction, it is noted that there are also cases of its correlation with squamous cell carcinomas in the mandible6, the behavior of ameloblastomas is considered more or less aggressive7. The diagnosis of this type of odontogenic tumor is histopathological and immunoistiquimic, whith positivity identified for CK19 and p634; BRAF V600E mutation RAS, FGFR2 or SMO7. Histopathological variations for World Health Organization, it is solid or multicystic and unicystic5,7. Subtypes as plexiform, desmoplastic, follicular and acanthomatous are described. Unictics type have a less aggressive behavior3. Jaw injuries are more frequent than in the maxilla. Recurrences are associated with mutations, which are more frequent in this region7. RefeRências
社论-牙源性肿瘤在牙科诊所也会发生吗?
在骨内病变中,我们经常发现根囊肿。由于牙髓的炎症过程和受累,它是已知的牙医。然而,当想到牙源性肿瘤时,可能会想到在常规X线片上经常发现的频繁、无痛的牙源性肿瘤。当复合物时很容易诊断。1但是其他来自牙齿组织的肿瘤呢?成釉细胞瘤是一种良性且相对常见的肿瘤(占牙源性肿瘤的10%至49%)1,2,3,起源于牙源性上皮,可能涉及上颌骨的软组织(外周成釉细胞癌)4或骨组织,在下颌骨的发病率较高,形式和组织病理学分型各不相同,在生命的第二和第三十年或以后的年轻人中观察到。1,2,3在放射学和成像方面,它们可能是单房或多房的,类似于囊性病变5,6或多个透亮区域2。成釉细胞瘤有几种组织病理学类型,诊断允许或多或少的侵入性治疗,因为它们往往经常复发7。从广泛手术造成的损伤和重建的需要来看,也有与下颌骨鳞状细胞癌相关的病例6,成釉细胞瘤的行为或多或少被认为具有攻击性7。这种类型的牙源性肿瘤的诊断是组织病理学和免疫组织化学的,其中CK19和p634阳性;BRAF V600E突变RAS、FGFR2或SMO7。世界卫生组织的组织病理学变异,它是固体或多囊体和单囊体5,7。描述了丛状、结缔组织增生性、滤泡性和棘皮瘤样的亚型。独行者的攻击性较低。颌骨损伤比上颌骨更常见。复发与突变有关,突变在该区域更为常见7。RefeRências
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