Hemichorea caused by non-ketotic hyperglycemia in a Sri Lankan woman: A case report

P. P. B. Herath, W. Kularatne
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Abstract

Basal ganglia are a subcortical set of nuclei, including the caudate nucleus, putamen, external and internal segments of globus pallidus, and associated structures including substantia nigra and subthalamic nucleus. Complex neuronal networks interconnect the basal ganglia and cortical motor areas. Chorea results due to a dysfunction within this neuronal network [1,2]. This disruption can occur as a result of direct structural damage, degeneration of selective sets of neurons, neurotransmitter receptor blockage, metabolic derangements, drug exposure, genetic mutations, and also due to underlying autoimmune conditions [1].
斯里兰卡妇女非酮症性高血糖所致血凝1例
基底神经节是皮层下的一组核,包括尾状核、壳核、苍白球内外段以及相关结构,包括黑质和丘脑底核。复杂的神经网络连接基底神经节和皮质运动区。舞蹈病的发生是由于该神经网络的功能障碍[1,2]。这种破坏可由于直接的结构损伤、选择性神经元的退化、神经递质受体阻塞、代谢紊乱、药物暴露、基因突变以及潜在的自身免疫性疾病而发生。
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