Immune Defenses of Colostrum and Milk in Human and Animals

M. El-Loly
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引用次数: 1

Abstract

The concept that milk, mammary secretions and the mammary gland have significant roles in immune defense is an old one. The bactericidal property of milk was recorded in the late nineteenth century. Also, observations at this time on the ability of milk to provide immunity to the newborn assumed a key role in the development of modern immunology. The mammalian neonate can’t to collect, chew, or digest solid food, depending completely on the colostrum of its mother and subsequently on milk for its survival. In addition to providing a complete diet with all the essential nutrients for the neonate through the initial period of its life, colostrum also gives basic immunological protection against surrounding pathogens. In ruminants specifically, for which no exchange of immune factors happens in uteri, colostrum and milk provide protection through high immunoglobulins (Igs) or antibodies content, without which the ruminant would not, survive Larson et al. [1].
人类和动物初乳和乳汁的免疫防御
牛奶、乳腺分泌物和乳腺在免疫防御中发挥重要作用的概念由来已久。牛奶的杀菌特性在19世纪末就有记载。此外,当时对牛奶为新生儿提供免疫力的能力的观察在现代免疫学的发展中发挥了关键作用。哺乳动物新生儿不能收集、咀嚼或消化固体食物,完全依赖母亲的初乳,随后依靠牛奶生存。除了在新生儿生命的最初阶段为其提供完整的饮食和所有必要的营养外,初乳还对周围的病原体提供基本的免疫保护。特别是在反刍动物中,由于子宫中没有发生免疫因子的交换,初乳和牛奶通过高免疫球蛋白(Igs)或抗体含量提供保护,没有这些,反刍动物就无法生存。Larson等人[1]。
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