Viewing the future research directions of heart failure from ge's phenotyping of heart failure with preserved ejection fraction

Q4 Medicine
Yan-xiang Zang, Wei-min Li, Qi Lou, H. Wang, Yu Duan
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引用次数: 0

Abstract

At present, guideline-directed medical therapy of heart failure (HF) has achieved certain results, but the evidence mostly focuses on HF with reduced ejection fraction, and there are some problems in the research on HF with preserved ejection fraction (HFpEF), such as inconsistent inclusion criteria and unconvincing results. Therefore, it may be more individualized and targeted to perform classification, typing, and treatment of HF from aspects such as pathogenesis, etiology, or pathophysiology, but not ejection fraction, especially HFpEF with strong heterogeneity. Ge's phenotyping of HFpEF is based on etiology and pathology, aiming at improving the outcome of HFpEF and exploring new approaches for the prognosis of HF.
从ge保留射血分数的心力衰竭表型看心力衰竭未来的研究方向
目前,指南指导的心力衰竭药物治疗已经取得了一定的效果,但证据大多集中在射血分数降低的心衰上,而射血分数保留的心衰研究也存在一些问题,如纳入标准不一致、结果不令人信服。因此,从发病机制、病因或病理生理学等方面对HF进行分类、分型和治疗可能更具个性化和针对性,但不包括射血分数,尤其是具有强异质性的HFpEF。Ge的HFpEF表型是基于病因和病理的,旨在改善HFpEF的预后,探索HF预后的新途径。
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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
24
审稿时长
32 weeks
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