Time to Hemostasis After Trauma and Transfusion by Patient Blood Type.

IF 2 Q2 NURSING

AACN Advanced Critical Care Pub Date : 2022-06-15 DOI:10.4037/aacnacc2022432

Justin L Miller, Hallie Harper, Hannah Jane McCarty, Peng Li, Allison R. Jones

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引用次数: 2

Abstract

BACKGROUND Although evidence supports an increased risk of mortality after major trauma among patients with type O blood, the relationship between patient blood type and clinical outcomes aside from mortality has not been fully elucidated. OBJECTIVE To examine the relationship between patient blood type and time to hemostasis after trauma and massive transfusion. METHODS A secondary analysis of the Pragmatic, Randomized Optimal Platelet and Plasma Ratios (PROPPR) trial was performed (N = 544). Blood type was dichotomized into type O versus non-type O. It was hypothesized that patients with non-type O blood would achieve hemostasis more quickly owing to the theoretical presence of increased clotting factors. Bivariate analysis and multiple Cox regression were conducted to test this assumption. RESULTS No significant difference was found in time to hemostasis between patients with type O blood and those with non-type O blood. However, mechanism of injury, diastolic blood pressure, and international normalized ratio affected the time to hemostasis in these trauma patients. CONCLUSION This study showed no significant difference in time to hemostasis by blood type.

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创伤后止血时间和按患者血型输血。

背景:尽管有证据支持O型血患者在重大创伤后死亡风险增加，但患者血型与除死亡率外的临床结果之间的关系尚未完全阐明。目的探讨创伤及大量输血后患者血型与止血时间的关系。方法对实用随机最佳血小板与血浆比率(PROPPR)试验(N = 544)进行二次分析。血型被分为O型血和非O型血。假设非O型血的患者会更快地止血，因为理论上存在更多的凝血因子。采用双变量分析和多重Cox回归对这一假设进行检验。结果O型血患者与非O型血患者止血时间差异无统计学意义。然而，损伤机制、舒张压、国际标准化比值对这些创伤患者的止血时间有影响。结论不同血型在止血时间上差异无统计学意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

AACN Advanced Critical Care NURSING-

CiteScore

2.10

自引率

4.50%

发文量

期刊介绍： AACN Advanced Critical Care is a quarterly, peer-reviewed publication of in-depth articles intended for experienced critical care and acute care clinicians at the bedside, advanced practice nurses, and clinical and academic educators. Each issue includes a topic-based symposium, feature articles, and columns of interest to critical care and progressive care clinicians. AACN Advanced Critical Care contains concisely written, practical information for immediate use and future reference. Continuing education units are available for selected articles in each issue. AACN Advanced Critical Care is an official publication of the American Association of Critical-Care Nurses.