Delivery of Curcumin Using Zein-Gum Arabic-Tannic Acid Composite Particles: Fabrication, Characterization, and in vitro Release Properties

IF 5.4 3区材料科学 Q2 CHEMISTRY, PHYSICAL

ACS Applied Energy Materials Pub Date : 2022-03-17 DOI:10.3389/fnut.2022.842850

Yiquan Zhang, Guiqiao Liu, F. Ren, Ning Liu, Yi Tong, Yi Li, An-Qi Liu, Lida Wu, Pengjie Wang

{"title":"Delivery of Curcumin Using Zein-Gum Arabic-Tannic Acid Composite Particles: Fabrication, Characterization, and in vitro Release Properties","authors":"Yiquan Zhang, Guiqiao Liu, F. Ren, Ning Liu, Yi Tong, Yi Li, An-Qi Liu, Lida Wu, Pengjie Wang","doi":"10.3389/fnut.2022.842850","DOIUrl":null,"url":null,"abstract":"The application of curcumin (Cur) in fat-free food is limited due to its poor water solubility, stability, and bioaccessibility. In this study, zein-gum arabic-tannic acid (zein-GA-TA) composite particles with high physical stability were fabricated to deliver Cur (ZGT-Cur). Their stability and in vitro release properties were also evaluated. The results showed that the thermal and photochemical stability of Cur was improved after loading into composite particles. Meanwhile, the retention rate of Cur in ZGT-Cur composite particles was enhanced compared with Z-Cur or ZG-Cur particles. Fourier transform infrared (FTIR) spectroscopy confirmed that the hydrogen bond within the particles was greatly enhanced after the addition of tannic acid (TA). The in vitro antioxidant activity of Cur in ZGT-Cur composite particles was higher in terms of 2,2'-azino-bis (ABTS) (93.64%) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) (50.41%) compared with Z-Cur or ZG-Cur particles. The bioaccessibility of Cur in ZGT-Cur composite particles was 8.97 times higher than that of free Cur. Therefore, the particles designed in this study will broaden the application of Cur in the food industry by improving its stability and bioaccessibility.","PeriodicalId":4,"journal":{"name":"ACS Applied Energy Materials","volume":null,"pages":null},"PeriodicalIF":5.4000,"publicationDate":"2022-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Energy Materials","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.3389/fnut.2022.842850","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}

引用次数: 6

Abstract

The application of curcumin (Cur) in fat-free food is limited due to its poor water solubility, stability, and bioaccessibility. In this study, zein-gum arabic-tannic acid (zein-GA-TA) composite particles with high physical stability were fabricated to deliver Cur (ZGT-Cur). Their stability and in vitro release properties were also evaluated. The results showed that the thermal and photochemical stability of Cur was improved after loading into composite particles. Meanwhile, the retention rate of Cur in ZGT-Cur composite particles was enhanced compared with Z-Cur or ZG-Cur particles. Fourier transform infrared (FTIR) spectroscopy confirmed that the hydrogen bond within the particles was greatly enhanced after the addition of tannic acid (TA). The in vitro antioxidant activity of Cur in ZGT-Cur composite particles was higher in terms of 2,2'-azino-bis (ABTS) (93.64%) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) (50.41%) compared with Z-Cur or ZG-Cur particles. The bioaccessibility of Cur in ZGT-Cur composite particles was 8.97 times higher than that of free Cur. Therefore, the particles designed in this study will broaden the application of Cur in the food industry by improving its stability and bioaccessibility.

查看原文本刊更多论文

用玉米胶-阿拉伯单宁酸复合颗粒递送姜黄素:制备、表征和体外释放特性

姜黄素的水溶性、稳定性和生物可及性较差，限制了其在无脂食品中的应用。本研究制备了具有高物理稳定性的玉米胶-阿拉伯单宁酸(zein-GA-TA)复合颗粒，用于输送Cur (ZGT-Cur)。并对其稳定性和体外释放性能进行了评价。结果表明，在复合颗粒中加入金属铈后，其热稳定性和光化学稳定性得到了改善。同时，与Z-Cur和ZG-Cur颗粒相比，ZGT-Cur复合颗粒中Cur的保留率有所提高。傅里叶变换红外光谱(FTIR)证实，加入单宁酸(TA)后，颗粒内的氢键明显增强。ZGT-Cur复合颗粒中2,2′-氮基-双(ABTS)和1,1-二苯基-2-吡啶酰肼(DPPH)的体外抗氧化活性均高于Z-Cur和ZG-Cur颗粒，分别为93.64%和50.41%。ZGT-Cur复合颗粒中Cur的生物可及性是游离Cur的8.97倍，因此，本研究设计的颗粒将通过提高其稳定性和生物可及性，拓宽Cur在食品工业中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

ACS Applied Energy Materials Materials Science-Materials Chemistry

CiteScore

10.30

自引率

6.20%

发文量

1368

期刊介绍： ACS Applied Energy Materials is an interdisciplinary journal publishing original research covering all aspects of materials, engineering, chemistry, physics and biology relevant to energy conversion and storage. The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrate knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important energy applications.