Elevation of α-1,3 fucosylation promotes the binding ability of TNFR1 to TNF-α and contributes to osteoarthritic cartilage destruction and apoptosis

IF 4.4 2区医学 Q1 RHEUMATOLOGY

Arthritis Research & Therapy Pub Date : 2022-02-09 DOI:10.1186/s13075-022-02776-z

Hanjie Yu, Mingxiu Li, Xiao‐dong Wen, Jie Yang, Xiaojun Liang, Xia Li, Xiao-Xue Bao, Jian Shu, Xiameng Ren, Wentian Chen, Zheng Li, Yi Li

引用次数: 6

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α-1,3聚焦化的升高促进TNFR1与TNF-α的结合能力，促进骨关节炎软骨破坏和细胞凋亡

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Arthritis Research & Therapy RHEUMATOLOGY-

CiteScore

8.30

自引率

2.00%

发文量

261

审稿时长

2.3 months

期刊介绍： Established in 1999, Arthritis Research and Therapy is an international, open access, peer-reviewed journal, publishing original articles in the area of musculoskeletal research and therapy as well as, reviews, commentaries and reports. A major focus of the journal is on the immunologic processes leading to inflammation, damage and repair as they relate to autoimmune rheumatic and musculoskeletal conditions, and which inform the translation of this knowledge into advances in clinical care. Original basic, translational and clinical research is considered for publication along with results of early and late phase therapeutic trials, especially as they pertain to the underpinning science that informs clinical observations in interventional studies.