Dermal substitute reinforced single-layer closure of the palatal fistula

Hardeep Singh, R. Khazanchi
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引用次数: 1

Abstract

Postoperative palatal fistulas are common after surgery to correct a cleft palate. The repair is hindered by palatoplasty-related scar tissue, reduced vascularity, and restricted mobility of flaps. Surgical repair of fistulae is often effective, but recurrence is common. A 3.5-year-old boy presented with anterior palatal fistula. The presence of peri-fistulous scarring prevented two-layered closure. Nasal layer closure was achieved but not the oral layer. The dermal matrix was reinforced in a one-step procedure over the nasal layer and fixed in place using a gel foam. At 6 months, the fistula almost completely healed, with only a pinpoint track remaining that occasionally leaked into the nasal cavity. These results indicate that the application of dermal matrix is a promising technique to repair fistula with surrounding scarring, but larger, prospective trials are needed to confirm its potential benefits.
真皮替代物强化单层腭瘘闭合
腭裂矫正术后腭瘘很常见。修复受到腭裂相关疤痕组织、血管减少和皮瓣活动受限的阻碍。瘘管的外科修复通常是有效的,但复发是常见的。一名3.5岁男孩出现腭前瘘管。瘘管周围瘢痕的存在阻止了两层闭合。鼻腔层闭合,但口腔层未闭合。真皮基质在鼻层上一步强化,并使用凝胶泡沫固定到位。6个月时,瘘管几乎完全愈合,只剩下一条精确的轨迹,偶尔会漏到鼻腔。这些结果表明,真皮基质的应用是一种很有前途的修复瘘管周围瘢痕的技术,但还需要更大规模的前瞻性试验来证实其潜在益处。
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16 weeks
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