Clinical effect of surgical removal combined with 5-aminolevulinic acid photodynamic therapy for plantar warts

中华医学美学美容杂志 Pub Date : 2019-08-15 DOI:10.3760/CMA.J.ISSN.1671-0290.2019.04.020

Xingfan Mo, R. Lu, Jingjing Li, Mingzhi Feng, Xiaoyan Chen, Minzhi Wu, Liang Zhao

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Abstract

Objective To observe the clinical efficacy of surgical operation combined with photodynamic therapy for plantar warts. Methods From July 2017 to June 2018, 16 patients with plantar warts were enrolled in the Department of Dermatology, the Fifth People's Hospital of Suzhou City. The enrolled patients aged 10 to 42 years, including 12 males and 4 females, with a course of 4 to 15 month, and a total of 47 plantar warts. The plantar warts was removed by surgical operation and bipolar coagulation, followed by the photodynamic treatment with 5-aminolevulinic acid for 3 to 4 times with an interval of 7-10 days. Results Eleven patients showed complete clearance after operation and three times photodynamic treatments, and the other 5 patients underwent 2 operations and four times photodynamic treatments. 47 plantar warts in 16 patients were disappeared completely during 6-month post-treatment follow up. The plantar warts clearance rate was 100%, and the skin texture still presented. In addition to local mild erythematous, pain and burning sensation presented after surgery, but no adverse reactions such as infection, ulcers and obvious scars occurred. Conclusions Surgery combined with 5-aminolevulinic acid photodynamic therapy is a favorable treatment for plantar warts. Key words: Metatarsus; Warts; Surgical procedures; Photodynamic therapy; Aminolevulinic acid

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手术切除联合5-氨基乙酰丙酸光动力疗法治疗足底疣的临床疗效

目的观察手术配合光动力疗法治疗足底疣的临床疗效。方法2017年7月至2018年6月，苏州市第五人民医院皮肤科收治足底疣患者16例。入选患者年龄为10至42岁，包括12名男性和4名女性，病程4至15个月，共有47个足底疣。通过外科手术和双相凝固去除足底疣，然后用5-氨基乙酰丙酸进行3至4次光动力治疗，间隔7-10天。结果11例患者经3次光动力治疗后完全清除，其余5例患者经2次光动力处理4次。16例患者的47个跖疣在治疗后6个月的随访中完全消失。足底疣的清除率为100%，皮肤纹理仍然存在。术后除局部出现轻度红斑、疼痛和烧灼感外，未出现感染、溃疡和明显瘢痕等不良反应。结论手术配合5-氨基乙酰丙酸光动力疗法是治疗足底疣的有效方法。关键词：跖骨；Warts；外科手术；光动力疗法；氨基乙酰丙酸

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来源期刊

中华医学美学美容杂志

自引率

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发文量

4641

期刊介绍： "Chinese Journal of Medical Aesthetics and Cosmetology" is a high-end academic journal focusing on the basic theoretical research and clinical application of medical aesthetics and cosmetology. In March 2002, it was included in the statistical source journals of Chinese scientific and technological papers of the Ministry of Science and Technology, and has been included in the full-text retrieval system of "China Journal Network", "Chinese Academic Journals (CD-ROM Edition)" and "China Academic Journals Comprehensive Evaluation Database". Publishes research and applications in cosmetic surgery, cosmetic dermatology, cosmetic dentistry, cosmetic internal medicine, physical cosmetology, drug cosmetology, traditional Chinese medicine cosmetology and beauty care. Columns include: clinical treatises, experimental research, medical aesthetics, experience summaries, case reports, technological innovations, reviews, lectures, etc.