Perspective on computer aided drug discovery for anti-SARS-CoV-2

Abstract

Objective To explore theresearch progress of the computer aided drug discovery for SARS-CoV-2 drugs. Methods Comprehensively searching internetresour-ces including news report,research papers in scientific journals and academic preprint websites. Results Since the outbreak of COVID-19, researchers in China and all over the world rapidly start to search drugs for anti-SARS-CoV-2and some progresses were made. This paper reviewed the progress of computer aided discovery of SARS-CoV-2 drugs. Conclusions Both docking and bioinformatics based methods had achievements and a number of candidate drugs have been identified, but more novel targets should be considered in the future. Key words: Novel coronavirus; SARS-CoV-2; Drug discovery